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Indiana vs. Ohio State - 10/3/15 College Football Pick, Odds, and Prediction

Ohio State Buckeyes (4-0) at Indiana Hoosiers (4-0)

College Football: Saturday, October 3, 2015 at 3:30 pm (Memorial Stadium)

The Line: Indiana Hoosiers +18.5 -- Over/Under: See the Latest Odds

TV: ABC, ESPN2

The Ohio State Buckeyes and Indiana Hoosiers square off Saturday at Memorial Stadium.

The Ohio State Buckeyes look to remain undefeated and pick up their second road victory. Cardale Jones is completing 57 percent of his passes for 622 yards, four touchdowns and four interceptions. Jones has thrown an interception in five of his last six games. Michael Thomas and Curtis Samuel have combined for 396 receiving yards and four touchdowns while Braxton Miller has seven receptions. The Ohio State Buckeyes ground game is averaging 231.5 yards per contest, and Ezekiel Elliott leads the way with 455 yards and five touchdowns. Defensively, OSU is allowing 12.3 points and 253.3 yards per game. Raekwon McMillan leads the Buckeyes with 40 tackles, Darron Lee has 2.5 sacks and Vonn Bell has pass deflections. Mike Weber and Parris Campbell are questionable.

Indiana vs. Ohio State - 10/3/15 College Football Pick, Odds, and Prediction

USA TODAY Sports

The Indiana Hoosiers look for a huge upset and improve to a 5-0 record. Nate Sudfeld is completing 61.1 percent of his passes for 1,143 yards, seven touchdowns and one interception. Sudfeld has a touchdown pass in six straight games. Ricky Jones and Simmie Cobbs Jr. have combined for 655 receiving yards and five touchdowns while Mitchell Paige has 11 receptions. The Indiana Hoosiers ground game is averaging 236.5 yards per contest, and Jordan Howard leads the way with 675 yards and four touchdowns. Defensively, Indiana is allowing 32 points and 499 yards per game. Marcus Oliver leads the Hoosiers with 28 tackles, Nick Mangieri has three sacks and Jonathan Crawford has two interceptions. Chase Dutra and Isaac James are questionable.

The Buckeyes are 37-15-1 ATS in their last 53 road games and 1-4 ATS in their last 5 games following a ATS loss. The Hoosiers are 1-4 ATS in their last 5 games in October and 4-0 ATS vs. a team with a winning record. The Buckeyes are 0-4 ATS in their last 4 meetings. 

Ohio State has played four games and has allowed three of those teams to hang around a lot longer than it would have liked. Indiana has an explosive offense and one of the top running backs in the country. If the Buckeyes continue to play average ball, Indiana will have little trouble covering in this matchup. 

Based on what we've seen so far, I'm siding with the points. 

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Indiana Hoosiers +18.5

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