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Colorado at USC - 10/8/16 College Football Pick, Odds, and Prediction

Colorado Buffaloes (4-1) at USC Trojans (2-3)

College Football: Saturday, October 8, 2016 at 4:00 pm (Los Angeles Memorial Coliseum)

The Line: USC Trojans -4.5 -- Over/Under: 63.5 See the Latest Odds

TV: PAC12

The Colorado Buffaloes and USC Trojans meet Saturday in a Pac-12 showdown at the Los Angeles Memorial Coliseum.

The Colorado Buffaloes look for their second road victory to build on their impressive 4-1 start to the season. Steven Montez is completing 63.2 percent of his passes for 743 yards, eight touchdowns and two interceptions. Montez and Sefo Liufau have combined for 14 touchdown passes. Shay Fields and Devin Ross have combined for 824 receiving yards and 10 touchdowns while Bryce Bobo has 17 receptions. The Colorado Buffaloes ground game is averaging 218.6 yards per contest, and Phillip Lindsay leads the way with 338 yards and six touchdowns. Defensively, Colorado is allowing 20.6 points and 290.4 yards per game. Kenneth Olugbode leads the Colorado Buffaloes with 34 tackles, Jimmie Gilbert has 4.5 sacks and Tedric Thompson has two interceptions.

Colorado at USC - 10/8/16 College Football Pick, Odds, and Prediction

USA TODAY Sports

The USC Trojans look for back-to-back wins for the first time this season to get back to a .500 record. Sam Darnold is completing 67.9 percent of his passes for 741 yards, five touchdowns and one interception. Darnold has moved the chains 31 times through the air on 55 completions. JuJu Smith-Schuster and Darreus Rogers have combined for 559 receiving yards and five touchdowns while Deontay Burnett has 17 receptions. The USC Trojans ground game is averaging 145.8 yards per contest, and Justin Davis leads the way with 384 yards and two touchdowns. Defensively, USC is allowing 27.4 points and 376.2 yards per game. Cameron Smith leads the USC Trojans with 45 tackles, Porter Gustin has two sacks and Jonathan Lockett has one interception.

The Buffaloes are 5-1 ATS in their last 6 road games and 6-0 ATS in their last 6 games overall. The Trojans are 2-6 ATS in their last 8 conference games and 3-8 ATS in their last 11 games overall. The home team is 4-0 ATS in their last 4 meetings.

Colorado took USC down to the wire last season and heads into this game looking like a better team than the Trojans. However, it's quite clear that USC has more talent than Colorado and should give the Buffaloes trouble on the defensive side. In two road games this season against Michigan and Oregon, Colorado has allowed a combined 83 points. You can argue USC has better skill position players than both of those teams. I'm not sure Colorado has enough horses to hang with a USC offense that found its groove last week by dropping 41 points on Arizona State.

Give me the USC Trojans and the small line at home. 

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USC Trojans -4.5

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