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Arizona Cardinals at San Francisco 49ers- 10/6/16 NFL Pick, Odds, and Prediction

Arizona Cardinals (1-3) at San Francisco 49ers (1-3)

NFL Football: Thursday, October 6, 2016 at 8:25 pm (Levi's Stadium)

The Line: San Francisco 49ers +3.5 -- Over/Under: 43 See the Latest Odds

TV:

The Arizona Cardinals look to get back on track after their third loss in four games as they travel to the Bay Area to face off with the San Francisco 49ers.

The Cardinals continue their frustrating start to the year as they take to the road to battle the Niners after dropping to 1-3 last week and 0-2 at home as they were woeful in a loss to the Los Angeles Rams and are quickly falling out of favour in the NFC playoff picture. Arizona was expected to be a Super Bowl contender this season but so far they have been exposed in a bad way as their offensive line has some big time holes and their offense hasn’t been able to get rolling outside of David Johnson, and now they are without Carson Palmer for this one. Drew Stanton will get the call and that may actually help the Cards here as they should be more conservative through the air and feed the rock to Johnson who should get well over 20 touches in this one and hope their defense can keep pace.

Arizona Cardinals at San Francisco 49ers- 10/6/16 NFL Pick, Odds, and Prediction

The NIners meanwhile are in a tailspin after a nice start to the season against the Rams but after dropping their third in a row they will look to avoid a fourth as they take on a Cards side that is going to be incredibly angry with how they have been playing. San Fran is also without Navarro Bowman for the rest of the year which is their only saving grace and the leader of their defense and now they are in big trouble and we should see that start here against Arizona. San Francisco also can’t get Blaine Gabbert going and calls in the locker room for Colin Kaepernick to start are getting louder and we could the polarizing pivot take the field at some point soon if Gabbert continues to struggle.

The Cards are 12-2 in their last 14 ATS on the road against a team with a losing home record, 1-4 ATS in their last five against the NFC, and 1-6 ATS in their last seven overall while the Niners are 5-0 ATS in their last five during week five, 3-8 ATS in their last 11 against a team with a losing record, and 2-6 ATS in their last eight overall. These two teams are both playing poorly but I think the road trip, even without Palmer, is a good spot for Arizona as they should have no issues moving the football on this Bowman-less defense and this is an absolute, cannot recover from, must win football game for the Cards. One last shot here, Arizona.

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Arizona Cardinals -3.5

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