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Arizona Cardinals vs. Seattle Seahawks - 10/23/16 NFL Pick, Odds, and Prediction

Seattle Seahawks (4-1) at Arizona Cardinals (3-3)

NFL Football: Sunday, October 23, 2016 at 8:30 pm (University of Phoenix Stadium)

The Line: Arizona Cardinals -1 -- Over/Under: 43.5 See the Latest Odds

TV: NBC

The Seattle Seahawks and Arizona Cardinals meet in a crucial NFC West showdown Sunday night at U of Phoenix Stadium on NBC.

The Seattle Seahawks look to build on their three-game winning streak and build their lead in the NFC West. The Seattle Seahawks have 11 regular season road victories since the 2014 NFL season. Russell Wilson is completing 65.9 percent of his passes for 1,334 yards, five touchdowns and one interception. Wilson has not thrown an interception in his last four games. Doug Baldwin and Jimmy Graham have combined for 716 receiving yards and three touchdowns while Tyler Lockett has 11 receptions. The Seattle Seahawks ground game is averaging 88.8 yards per contest, and Christine Michael leads the way with 354 yards and four touchdowns. Defensively, Seattle is allowing 15.6 points and 283.6 yards per game. Bobby Wagner leads the Seattle Seahawks with 44 tackles, Cliff Avril has four sacks and Earl Thomas has two interceptions.

Arizona Cardinals vs. Seattle Seahawks - 10/23/16 NFL Pick, Odds, and Prediction

USA TODAY Sports

The Arizona Cardinals look for their third straight victory to get right back in the NFC West division race. The Arizona Cardinals have won six of their last nine home games with two coming this season. Carson Palmer is completing 60.4 percent of his passes for 1,363 yards, seven touchdowns and five interceptions. Palmer has two touchdown passes in his last three games. Larry Fitzgerald and John Brown have combined for 711 receiving yards and five touchdowns while David Johnson has 20 receptions. The Arizona Cardinals ground game is averaging 124.3 yards per contest, and Johnson leads the way with 568 yards and eight touchdowns. Defensively, Arizona is allowing 17.3 points and 295 yards per game. Tony Jefferson leads the Arizona Cardinals with 48 tackles, Markus Golden has six sacks and Marcus Cooper has three interceptions.

The Seahawks are 1-4 ATS in their last 5 vs. NFC and 20-41-2 ATS in their last 63 games in October. The Cardinals are 2-8 ATS vs. a team with a winning record and 3-8 ATS in their last 11 home games. The Seahawks are 5-2 ATS in their last 7 meetings and the over is 10-2 in the last 12 meetings in Arizona.

The road team has won five of the last six games between the Seahawks and Cardinals. However, Russell Wilson continues to look like he's playing on one leg and hasn't exactly been the difference maker we're used to seeing him be. Playing an Arizona Cardinals defense that is quick and rushes the passer extremely well isn't the type of defense you want to face when banged up. Wilson is a sitting duck against this Arizona defense if he's not able to move out of the pocket and make plays with his legs. I'm also sure the Arizona Cardinals had this game circled after getting beat down last year at home by the Seattle Seahawks that cost them the NFC West division.

In a toss-up game, I'm siding with the Cardinals at home.

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Arizona Cardinals -1

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