CFB Picks: Pittsburgh vs. Louisville - 9/26/20 College Football Pick, Odds, and Prediction

CFB Picks: Pittsburgh vs. Louisville - 9/26/20 College Football Pick, Odds, and Prediction Photo by Jamie Rhodes-USA TODAY Sports

Louisville Cardinals (1-1) at Pittsburgh Panthers (2-0)

College Football: Saturday, September 26, 2020 at 12:00 pm (Heinz Field)

The Line: Pittsburgh Panthers -2.5 -- Over/Under: 53 Click Here for the Latest Odds

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The Louisville Cardinals and the Pittsburgh Panthers meet Saturday in college football action from Heinz Field. 

Louisville enters this game at 1-1 on the young 2020 season. The Cardinals took a 35-21 win over Western Kentucky in their opener, but then fell to Miami 47-34 this past weekend. As for the Panthers, they’re coming in at 2-0. Pittsburgh drilled Austin Peay 55-0 in Week 1 and then took out Syracuse 21-10 in their last game. Check back all season long for free college football picks and college football predictions at Sports Chat Place. 

The Cardinals posted a nice effort versus Western Kentucky in the opener, going up 28-7 by halftime and never looking back. Louisville quarterback Malik Cunningham put up 343 yards on 19-of-34 passing for three touchdowns and an interception. Leading the receivers in that one were Dez Fitzpatrick and Braden Smith, who each had four catches for 110 yards (and Fitzpatrick scored). 

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In Week 2, Louisville couldn’t keep up with Miami in the first half, falling behind 20-6 at the break, The Cardinals scored 28 points in the second half, but also allowed 27. Cunningham threw for 307 yards, three touchdowns and a pick in that one, and Chatarius Atwell had 114 yards and two TDs on eight catches. Javian Hawkins led the rush with 164 yards and a TD. 

Over on the Panthers’ side, they’re looking pretty solid so far. The big opener win versus Austin Peay wasn’t even close, as Pitt jumped out to a 42-0 lead at halftime. Panthers QB Kenny Pickett posted 277 yards and a touchdown in that one, and Vincent Davis led the way rushing with 43 yards and two touchdowns. 

In the Syracuse game, Pittsburgh had a little more trouble but were still in control for most of the day. Pickett finished with 215 yards, two touchdowns and an interception in that game, and Davis had 53 yards on 18 carries. Tops in receiving were Jared Wayne and Jordan Addison, who combined for 12 receptions, two touchdowns and 116 yards. 

The Cardinals are 4-0 ATS in their last four games after an ATS loss and 4-1 ATS in their last five games overall. Louisville is 3-7 ATS in their last 10 games after a straight-up win and 4-11 ATS in their last 15 games in the conference. 

Meanwhile, Pitt is 4-1 ATS in their last five games in September and 5-2 ATS versus a team with a winning record. The Panthers are 9-4 ATS in their last 13 games after an ATS win and 8-20 ATS in their last 28 games as a home favorite. 

Pick: I like the Cardinals in this one. Louisville has displayed some nice offensive capabilities so far, with 69 points between their two games. The defense has had a few issues allowing points though, so this one could end up being a high-scoring affair. Overall these teams match up pretty well and it will be an interesting game. By most indications, it should be a close finish as well. 

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Andrew’s Pick Louisville Cardinals +2.5

The pick in this article is the opinion of the writer, not a Sports Chat Place site consensus.

Mitch's Take...

Louisville at Pitt - Saturday 9/26/20 - College Football Picks & Prediction | Sports Chat Place (skip to 58s)