Louisville vs James Madison 11/5/22 College Football Picks, Predictions, Odds

The Louisville Cardinals and James Madison Dukes do battle Saturday afternoon in week 10 college football action at Cardinal Stadium. The James Madison Dukes look to build on their 5-2 start. The Louisville Cardinals look to build on their 3-game winning streak.

The James Madison Dukes have won 2 of their last 3 road games. Todd Centeio is completing 64 percent of his passes for 1,780 yards, 17 touchdowns and 4 interceptions. Kris Thornton and Reggie Brown have combined for 1,035 receiving yards and 8 touchdowns, while Terrance Greene Jr. has 15 receptions. The James Madison Dukes ground game is averaging 195.3 yards per contest, and Percy Agyei-Obese leads the way with 556 yards and 4 touchdowns. Defensively, James Madison is allowing 20.9 points and 293.3 yards per game. Taurus Jones leads the James Madison Dukes with 58 tackles, Isaac Ukwu has 5 sacks and Jailin Walker has 2 interceptions.

The Louisville Cardinals have won 3 straight home games. Malik Cunningham is completing 60.9 percent of his passes for 1,254 yards, 5 touchdowns and 4 interceptions. Tyler Hudson and Ahmari Huggins-Bruce have combined for 903 receiving yards and 1 touchdown, while Marshon Ford has 21 receptions. The Louisville Cardinals ground game is averaging 197.1 yards per contest, and Cunningham leads the way with 541 yards and 11 touchdowns. Defensively, Louisville is allowing 20.6 points and 365.3 yards per game. Momo Sanogo leads the Louisville Cardinals with 47 tackles, YaYa Diaby has 5.5 sacks and Jarvis Brownlee has 2 interceptions.

The Dukes are 1-9 ATS vs. a team with a winning record and 5-2 ATS in their last 7 games overall. The Cardinals are 14-29-1 ATS vs. a team with a winning record and 4-1 ATS in their last 5 games overall. The over is 5-1 in Dukes last 6 games overall. The over is 4-1 in Cardinals last 5 games in November.

The James Madison Dukes are a solid team on paper, but they’re coming off two bad losses and now travel to a place that’s tough to play. The Louisville Cardinals are playing their best ball of the season right now, and that includes upsetting a top-10 team in the country. Louisville is becoming more consistent offensively, and its defense is now top-25 in scoring. This isn’t a spot where James Madison bounces back. Things likely get worse. Give me Louisville in a comfortable home victory.