Buffalo vs Troy Prediction Football Picks Today 9/20/25

Buffalo and Troy meet Saturday in Week 4 college football action from UB Stadium.  Here’s a Buffalo vs Troy prediction. We will look at this from a betting perspective and determine the best Buffalo vs Troy pick. 

Troy is Struggling

Troy is really struggling heading into this game. In the first game of the season, Troy was able to secure the 38-20 victory over Nicholls. Two games ago against Clemson, Troy was competitive, but ended up losing 27-16. At halftime, Troy was up 16-3, and in the second half the offense just died, and that led to the loss. In the last agme against Memphis, Troy scored only seven points, while the defense gave up 28 points, and it was another loss. Troy had 112 total yards, and only 72 through the air. The offense has looked awful the last couple of games, and they need to find a way to get the offense out to a faster start here. Tucker Kilcrease completed 10 of his 29 passes for 65 yards, zero touchdowns, and one interception. 


Troy on the season is averaging 20.33 points while their defense is giving up 25 points per game. The offense is ranked 106th and it just hasn’t been good enough. They need to find a way to get the passing game going. 

Why Troy Will Beat Buffalo

How Good or Bad is Buffalo?

Through three games, it’s still hard to get a real good feel on how good or bad Buffalo is. Heading into the season there were a lot of expectations surrounding this Buffalo team, and they come into this game with a 2-1 record, but one of the wins, was almost an awful loss. In the last game against Kent State, Buffalo needed a late touchdown to beat a team that many believe might not win another game this season. The most important thing is they picked up a win though. Ta’Quan Roberson had a huge game completing 28 of his 40 passes for 318 yards, three touchdowns, and one interception. Al-Jay Henderson had a huge game, finishing with 15 carries for 75 yards and a touchdown. 

Buffalo on the season is averaging 28.67 points while their defense is giving up 19 points per game. The offense is ranked 73rd in all of college football while the defense is ranked 53rd. In this game, the defense is going to need to be good. 

Why Buffalo Will Beat Troy

Buffalo vs Troy Prediction

This total is just a bit too high. Troy’s offense was good in the first two games, but the last six quarters, the offense has been a major issue. Over the last six quarters they have scored only seven points total, and their offense is going to be a major issue here. For Buffalo I expect their defense is going to be motivated and it wouldn’t shock me if Troy finished with seven or less points. I am not as sold on this Buffalo offense as much as I was at the beginning of the season, and they also won’t be running up the score. Neither team is reaching 24 points here. Back the under to cash. 

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