Houston vs Arizona Prediction Football Picks Today 10/18/25

The Arizona Wildcats and Houston Cougars meet Saturday in college football action at TDECU Stadium. Here’s a Houston vs Arizona Prediction. This article will include a Houston vs Arizona Pick.

Arizona Wildcats Betting Preview

The Arizona Wildcats beat Oklahoma State, lost to BYU, and plays Colorado next. The Arizona Wildcats have split their last 10 games. Noah Fifita is completing 62.7 percent of his passes for 1,560 yards, 15 touchdowns, and 4 interceptions. Javin Whatley and Kris Hutson have combined for 590 receiving yards and 5 touchdowns, while Chris Hunter has 17 receptions.


The Arizona Wildcats ground game is averaging 47.2 yards per contest, and Ismail Mahdi leads the way with 403 yards and 1 touchdown. Defensively, Arizona is allowing 18.5 points and 275.7 yards per game. Dalton Johnson leads the Arizona Wildcats with 41 tackles, Riley Wilson has 3 sacks and Jay’Vion Cole has 2 interceptions.

Houston Cougars Betting Preview

The Houston Cougars beat Oklahoma State, lost to Texas Tech, and they play Arizona State next. The Houston Cougars have won 5 of their last 6 games. Conner Weigman is completing 61.5 percent of his passes for 1,216 yards, 8 touchdowns, and 2 interceptions. Amare Thomas and Tanner Koziol have combined for 751 receiving yards and 4 touchdowns, while Stephon Johnson has 13 receptions.

The Houston Cougars ground game is averaging 159.2 yards per contest, and Dean Connors leads the way with 438 yards and 4 touchdowns. Defensively, Houston is allowing 17.5 points and 306.5 yards per game. Jalen Garner leads the Houston Cougars with 42 tackles, Corey Platt Jr. has 2.5 sacks and C.J. Douglas has 1 interception.

Why the Houston Cougars will win

Why the Arizona Wildcats will win

Total Points Facts

Houston Cougars Player Prop Facts

Arizona Wildcats Player Prop Facts

Matchup/League Facts

Houston vs Arizona Prediction

Arizona appears to be an underrated team with a decent offense, but it’s the defense that’s been surprising and makes the points worth a look. However, Arizona has been on the road just once this season, and that was an ugly showing against Iowa State. Houston is far and away more battle tested, has the defense and physicality to match Arizona, and its offense has come along over the last month.

Houston has covered 5 of its last 6 games as a favorite, while Arizona has failed to cover 7 of its last 9 games as an underdog. We’re not being asked to lay anything crazy. Give me Houston and the small number at home.

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