Iowa State vs Arizona Prediction Football Picks Today 9/27/25

The Arizona Wildcats and Iowa State Cyclones meet Saturday in college football action at Jack Trice Stadium. Here’s a Iowa State vs Arizona Prediction. This article will include a Iowa State vs Arizona Pick.

Arizona Wildcats Betting Preview

The Arizona Wildcats beat Weber State and Kansas State, and plays Oklahoma State next. The Arizona Wildcats have won 4 of their last 6 games. Noah Fifita is completing 59 percent of his passes for 712 yards, 6 touchdowns, and 0 interceptions. Javin Whatley and Luke Wysong have combined for 334 receiving yards and 2 touchdowns, while Brandon Phelps has 5 receptions.

The Arizona Wildcats ground game is averaging 189 yards per contest, and Ismail Mahdi leads the way with 263 yards and 1 touchdown. Defensively, Arizona is allowing 8.7 points and 222.3 yards per game. Genesis Smith leads the Arizona Wildcats with 19 tackles, Chase Kennedy has 2 sacks and Gavin Hunter has 1 interception.

Iowa State Cyclones Betting Preview

The Iowa State Cyclones beat Arkansas State and Iowa, and they play Cincinnati next. Iowa State has won 8 of its last 9 games. Rocco Becht is completing 65 percent of his passes for 860 yards, 7 touchdowns, and 1 interception. Brett Eskildsen and Gabe Burkle have combined for 311 receiving yards and 2 touchdowns, while Xavier Townsend has 7 receptions.

The Iowa State Cyclones ground game is averaging 161 yards per contest, and Carson Hansen leads the way with 252 yards on 54 carries. Defensively, Iowa State is allowing 14.3 points and 297 yards per game. Marcus Neal Jr. leads the Iowa State Cyclones with 29 tackles, Tamatoa McDonough has 2 sacks and Jeremiah Cooper has 1 interception.

Arizona Wildcats @ Iowa State Cyclones Betting Trends: Week 5

 

Why the Iowa State Cyclones will win

Why the Arizona Wildcats will win

Total Points Facts

Iowa State Cyclones Player Prop Facts

Arizona Wildcats Player Prop Facts

Matchup/League Facts

Iowa State vs Arizona Prediction

Iowa State is the more proven team at home with the star quarterback, so the line is what it is. However, Iowa State has played a lot of games close to the vest and hasn’t been able to finish drives offensively the way you’d expect. All three games for Iowa State against FBS opponents have been decided by single digits.

Arizona just got a nice home win over Kansas State, is balanced offensively, and has one of the best defenses in the country. Arizona is seventh in total defense and sixth in scoring defense. It doesn’t feel like Arizona is getting much respect. I’ll grab the points.

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