Mississippi State vs Missouri Prediction 11/15/25 College Football Picks Today

In this article, we will formulate a Mississippi State vs Missouri Prediction for this College Football Week 12 game on Saturday, November 15th. Let’s take a look at the prediction for this College Football matchup.

Missouri Tigers Preview

Missouri has a 6-3 record this season and is sitting 9th in the SEC. They are 4-4-1 ATS, 5-4-0 in Over/Under and have a 5-2 home record and a 1-1 away record. Missouri is coming off a 17-38 home loss against Texas A&M and will face Mississippi State, Oklahoma and Arkansas next.

Offensively, Missouri averages 33.3 points per game, ranking 30th in the nation, while defensively, they allow 19.1 points per game, which is 21st. Missouri averages 451.8 total yards per game (219.4 passing and 232.4 rushing), while allowing 270.0 total yards per game (107.3 rushing and 162.7 passing).

Beau Pribula leads Missouri with 1,685 passing yards with 69.6% completed passes and 11 touchdowns. Jamal Roberts leads the team in rushing yards with 538, while Marquis Johnson has a team-high 28 receptions for 340 receiving yards. Defensively, Josiah Trotter has a team-high 59 total tackles (30 of them solo), while Damon Wilson II leads the team in sacks, with 6.5.

Mississippi State Bulldogs Preview

Mississippi State has a 5-5 record this season and is sitting 13th in the SEC. They are 8-2-0 ATS, 5-5-0 in Over/Under and have a 3-3 home record and a 2-2 away record. Mississippi State is coming off a 21-41 home loss against Georgia and will face Missouri and Ole Miss next.

Offensively, Mississippi State averages 32.0 points per game, ranking 48th in the nation, while defensively, they allow 26.3 points per game, which is 85th. Mississippi State averages 399.6 total yards per game (242.8 passing and 156.8 rushing), while allowing 388.7 total yards per game (176.2 rushing and 212.5 passing).

Blake Shapen leads Mississippi State with 2,234 passing yards with 65.2% completed passes and 15 touchdowns. Davon Booth leads the team in rushing yards with 513, while Anthony Evans III has a team-high 56 receptions for 680 receiving yards. Defensively, Jahron Manning has a team-high 70 total tackles (28 of them solo), while Will Whitson leads the team in sacks, with 2, and Brylan Lanier has a team-high 3 interceptions.

Mississippi State Bulldogs @ Missouri Tigers Betting Trends: Week 12

 

Why the Missouri Tigers will win

Why the Mississippi State Bulldogs will win

Total Points Facts

Missouri Tigers Player Prop Facts

Mississippi State Bulldogs Player Prop Facts

Matchup/League Facts

Mississippi State vs Missouri Prediction

In this Mississippi State vs Missouri Prediction, Missouri is coming as -7-point home favorites, with the total set at 51.5 points. Both teams have almost the same number of wins this season and are both coming into this matchup in poor form. Missouri is 1-3 in its last 4 games and 1-4-1 against the spread in its last 6, while Mississippi State is 1-5 in its last 6 and 8-2 against the spread this season. Missouri has been a top-30 team both offensively and defensively this season, winning by an average of 14.2 points per game. The value here lies with the home team, so take Missouri and lay the -7 points.

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