South Carolina vs Vanderbilt Prediction Football Picks Today 9/13/25

The Vanderbilt Commodores and South Carolina Gamecocks meet Saturday in college football action at Williams-Brice Stadium. Here’s a South Carolina vs Vanderbilt Prediction. This article will include a South Carolina vs Vanderbilt Pick.

Vanderbilt Commodores Betting Preview

The Vanderbilt Commodores beat Charleston Southern and Virginia Tech, and they play Georgia State next. The Vanderbilt Commodores have won 3 straight games. Diego Pavia is completing 74.4 percent of his passes for 468 yards, 5 touchdowns, and 1 interception. Tre Richardson and Eli Stowers have combined for 243 receiving yards and 2 touchdowns, while Junior Sherrill has 5 receptions.

The Vanderbilt Commodores ground game is averaging 231.5 yards per contest, and Sedrick Alexander leads the way with 156 yards and 2 touchdowns. Defensively, Vanderbilt is allowing 11.5 points and 191.5 yards per game. Martel Hight leads the Vanderbilt Commodores with 7 tackles, Hayden Bray has 1 sack and CJ Heard has 1 interception.

South Carolina Gamecocks Betting Preview

The South Carolina Gamecocks beat Virginia Tech and South Carolina State, and will play Missouri next. The South Carolina Gamecocks have won 8 straight regular season games. LaNorris Sellers is completing 60.5 percent of his passes for 337 yards, 2 touchdowns, and 0 interceptions. Nyck Harbor and Donovan Murph have combined for 159 receiving yards and 1 touchdown, while Vandrevius Jacobs has 4 receptions.

The South Carolina Gamecocks ground game is averaging 122 yards per contest, and Oscar Adaway III leads the way with 80 yards and 1 touchdown. Defensively, South Carolina is allowing 10.5 points and 303 yards per game. Fred Johnson leads the South Carolina Gamecocks with 13 tackles, Dylan Stewart has 2 sacks and Peyton Williams has 1 interception.

Vanderbilt Commodores @ South Carolina Gamecocks Betting Trends: Week 3

Why the South Carolina Gamecocks will win

Why the Vanderbilt Commodores will win

Total Points Facts

South Carolina Gamecocks Player Prop Facts

Vanderbilt Commodores Player Prop Facts

Matchup/League Facts

South Carolina vs Vanderbilt Prediction

Vanderbilt has covered 10 of its last 12 games as an underdog, and 6 of those covers were outright victories. You can talk yourself into the points in this SEC showdown. However, it feels like South Carolina is getting a soft line because of Vanderbilt has been a killer as an underdog lately.

South Carolina is the better, deeper team across the board with a Heisman caliber quarterback leading the charge, and the Gamecocks smoked the Commodores on the road back in November, 28-7. I’m not trying to step in front of this South Carolina squad, especially at home with the small chalk. I’ll take South Carolina by a touchdown on Saturday.

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