USC vs Louisiana Prediction Football Picks Today 9/12/26

In this article we will formulate a USC vs Louisiana prediction for this College Football game on Saturday, September 12th at Los Angeles Memorial Coliseum in Los Angeles, California. Let’s take a look at the prediction for this Week 2 matchup. 

USC Trojans Betting Preview

The USC Trojans are 2-0 this season after they defeated Fresno State by a score of 39-0 in week one. USC led 30-0 at halftime and they added nine points in the second half in the shutout win. The Trojans out gained Fresno State by a total of 552-116, went 5-8 on third downs, and tied the turnover battle at two in the game. Jayden Maiava threw for 349 yards and three touchdowns, while Trent Mosley caught four passes for 104 yards and two scores. Waymond Jordan rushed 11 times for 67 yards and one touchdown in the win. 

Prior to that game, USC defeated San Jose State by a score of 42-26 in week zero. USC led 28-0 at halftime, but they allowed 26 points in the second half in the win. The Trojans out gained SJSU by a total of 505-336, went 9-13 on third downs, and lost the turnover battle by a total of 1-0 in the game. Maiava threw for 286 yards and two touchdowns, while Trent Mosley caught seven passes for 118 yards and one score in the game. 

Louisiana Ragin’ Cajuns Betting Preview

The Louisiana Ragin’ Cajuns are 1-0 this year after they defeated Lamar by a score of 38-7 last week. Louisiana led 28-0 at halftime and cruised to the easy win in the second half. The Ragin’ Cajuns out gained Lamar by a total of 474-205, went 3-8 on third downs, and won the turnover battle by a total of 4-3 in the game. Lunch Winfield threw for 189 yards and two interceptions, while Caden Jensen caught five passes for 77 yards. Darrell Smith rushed 10 times for 84 yards and two scores in the win. 

Last year, Louisiana went 6-7 (5-3) and they finished tied for second in the Sun Belt West standings. Louisiana opened the season with a 14-12 loss against Rice, but did beat McNeese by a score of 34-10 after that. The Ragin’ Cajuns were just 2-6 through eight games, but they won four games in a row to end the regular season, before losing to Delaware by a score of 20-13 in the 68 Ventures Bowl. 

Why the USC Trojans will win

Why the Louisiana Ragin’ Cajuns will win

Total Points Facts

USC Trojans Player Prop Facts

Louisiana Ragin’ Cajuns Player Prop Facts

Matchup/League Facts

USC vs Louisiana Prediction 

USC comes into this matchup as another huge favorite, as they continue their very soft non-conference schedule. The Trojans dominated Fresno State last week and the defense played a full 60 minutes. Louisiana did get a win last week as well, but this is a big difference in competition. I don’t see how ULL is going to move the ball in this game, while I also struggle to see them getting many stops. Take USC to win big at home. 

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