Vanderbilt vs Kentucky Prediction Football Picks Today 11/22/25

The Kentucky Wildcats and Vanderbilt Commodores meet Saturday in college football action at FirstBank Stadium. Here’s a Vanderbilt vs Kentucky Prediction. This article will include a Vanderbilt vs Kentucky Pick.

Kentucky Wildcats Betting Preview

The Kentucky Wildcats beat Florida and Tennessee Tech, and they play Louisville next. Kentucky has won 3 straight games. Cutter Boley is completing 68.8 percent of his passes for 1,780 yards, 13 touchdowns, and 8 interceptions. Kendrick Law and Hardley Gilmore IV have combined for 751 receiving yards and 4 touchdowns, while Willie Rodriguez has 16 receptions.

The Kentucky Wildcats ground game is averaging 159.9 yards per contest, and Seth McGowan leads the way with 693 yards and 12 touchdowns. Defensively, Kentucky is allowing 23.1 points and 344.6 yards per game. Ty Bryant leads the Kentucky Wildcats with 56 tackles, Steven Soles Jr. has 3.5 sacks and Jordan Lovett has 2 interceptions.

Vanderbilt Commodores Betting Preview

The Vanderbilt Commodores beat Auburn, lost to Texas, and they play Tennessee next. The Vanderbilt Commodores have won 3 of their last 4 games. Diego Pavia is completing 70 percent of his passes for 2,440 yards, 21 touchdowns, and 5 interceptions. Eli Stowers and Junior Sherrill have combined for 1,139 receiving yards and 10 touchdowns, while Tre Richardson has 28 receptions.

The Vanderbilt Commodores ground game is averaging 185.2 yards per contest, and Diego Pavia leads the way with 613 yards and 7 touchdowns. Defensively, Vanderbilt is allowing 22.2 points and 357.2 yards per game. Bryan Longwell leads the Vanderbilt Commodores with 58 tackles, Miles Capers has 4.5 sacks and Martel Hight has 1 interception.

Why the Vanderbilt Commodores will win

Why the Kentucky Wildcats will win

Total Points Facts

Vanderbilt Commodores Player Prop Facts

Kentucky Wildcats Player Prop Facts

Matchup/League Facts

Vanderbilt vs Kentucky Prediction

Vanderbilt has been the more consistent team this season, is 7-2-1 ATS and has the offense to give Kentucky the business. However, Kentucky has turned its season around over the last three weeks and finds itself one win away from a bowl berth. Kentucky has covered 4 of its last 5 games and has outright won its last 2 games as an underdog. There’s a lot of hype around Vanderbilt, but this is a program that’s also 5-11 ATS in its last 16 games when a favorite of 7 or more points. Kentucky looked dead in the water after a 2-5 record, but this should be a motivated group. I’ll grab the points.

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