Draftkings MLB DFS Picks: Athletics vs. Twins 8/21/25

Major League Baseball presents Draftkings baseball fans with an American League matchup featuring the Athletics and the Minnesota Twins. Let’s take a look at this MLB game from a DFS perspective.

Before we dive into the Athletics vs. Minnesota Twins game let’s review the rules for the Draftkings MLB single game showdown contest.

Draftkings Single Game Showdown Contest Rules

You have $50,000 to utilize on five players from either team. However, one of those players will be designated as your team captain. The captain accumulates 1.5 times the standard fantasy points. Additionally, the captain is 1.5 times the standard cost of the flex position.

The remaining four players in your lineup will receive the standard fantasy points. Having stated that, it is highly important for you to identify the correct player for your captain position if you hope to win a large field DFS GPP (guaranteed prize pool) showdown contest.

If you have additional questions regarding the rules for the single game showdown contest, I recommend that you check out the Draftkings website for more details.

*I recommend that all readers review the starting lineups for both teams prior to setting your DFS lineup for this one game slate.

Here are my Draftkings picks for this afternoon’s Athletics vs. Minnesota Twins matchup.

Draftkings MLB DFS Picks

Captain-Jack Perkins, Starting Pitcher, Athletics $11,000

On Thursday afternoon, Major League Baseball presents the third game of a three-game American League series featuring the Athletics and the Minnesota Twins.

How are these two teams playing entering today’s MLB game? The Athletics arrive at the third game of this three-game series with the Minnesota Twins playing good baseball. The Athletics have won five of the team’s last seven games played in the 2025 MLB regular season, including a convincing 10-3 win over the Los Angeles Angels last week.

Conversely, the Minnesota Twins arrive at today’s American League game playing below average baseball. More specifically, the Twins have lost five of the team’s last six games played in the 2025 MLB regular season, including an 8-5 loss to the Detroit Tigers five days ago.

Now that we have determined how both of these teams are currently playing let’s turn our attention to this afternoon’s contest. Starting pitcher Jack Perkins has been a solid performer for the Athletics starting pitching rotation recently. Having stated that, how has Perkins performed from a statistical standpoint this season? Let’s review the Perkins relevant game data from the 2025 MLB regular season to answer that question.

Through 11 starts made this season, Athletics starting pitcher Jack Perkins has amassed a robust 2-2 (win-loss record), a 4.28 ERA (Earned Run Average) and a 1.13 WHIP (Walks and Hits per Inning Pitched). It should also be noted that Jack Perkins has tallied 35 strikeouts while allowing 14 walks in 33.2 innings pitched this season.

More recently, in the Athletics dominant 13-3 win over the Los Angeles Angels six days ago, Athletics starting pitcher Jack Perkins certainly pitched at a high-level. Perkins pitched five quality innings while scattering five hits and one walk in the Athletics defeat of the Los Angeles Angels.

In my view, Jack Perkins is the most likely player to post the most Draftkings points in this MLB regular season game. For that specific reason, I am backing Athletics starting pitcher Jack Perkins at the captain position for this one game MLB DFS slate.

Flex plays I like to play well in this MLB regular season contest (Draftkings price noted): Jose Urena, Starting Pitcher (Minnesota Twins) $10,000: Nick Kurtz, First Baseman (Athletics) $10,600: Shea Langeliers, Catcher (Athletics) $10,200.

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