Draftkings MLB Showdown Picks: Brewers vs. Padres 9/24/25

Major League Baseball presents Draftkings baseball fans with a National League matchup featuring the Milwaukee Brewers and the San Diego Padres. Let’s take a look at this MLB game from a DFS perspective.

Before we dive into the Milwaukee Brewers vs. San Diego Padres game let’s review the rules for the Draftkings MLB single game showdown contest.


Draftkings Single Game Showdown Contest Rules

You have $50,000 to utilize on five players from either team. However, one of those players will be designated as your team captain. The captain accumulates 1.5 times the standard fantasy points. Additionally, the captain is 1.5 times the standard cost of the flex position.

The remaining four players in your lineup will receive the standard fantasy points. Having stated that, it is highly important for you to identify the correct player for your captain position if you hope to win a large field DFS GPP (guaranteed prize pool) showdown contest.

If you have additional questions regarding the rules for the single game showdown contest, I recommend that you check out the Draftkings website for more details.

*I recommend that all readers review the starting lineups for both teams prior to setting your DFS lineup for this one game slate.

Here are my Draftkings picks for this afternoon’s Brewers vs. Padres matchup.

Draftkings MLB Showdown Picks

Captain-Dylan Cease, Starting Pitcher, San Diego Padres $11,400

On Wednesday afternoon, Major League Baseball presents the final game of a three-game National League series featuring the Milwaukee Brewers and the San Diego Padres.

How are these two teams playing entering this MLB game? The San Diego Padres arrive at the third game of this three-game series playing good baseball. The Padres have won four of the team’s last five games played in the 2025 MLB regular season, including a 3-2 victory over the Chicago White Sox three days ago.

In direct contrast to the San Diego Padres, the Milwaukee Brewers arrive at today’s National League game playing below average baseball. The Brewers have lost four of the team’s last five games played this season, including a 7-1 loss to the St. Louis Cardinals last week.

Now that we have determined how both of these teams are currently playing let’s shift our focus to this afternoon’s contest. Starting pitcher Dylan Cease has certainly been a solid performer for the San Diego Padres starting pitching rotation this season. Having stated that, how has Cease pitcher performed from a statistical standpoint? Let’s review Cease’s relevant game data from the 2025 MLB regular season to answer that question.

In 31 starts made this season, San Diego Padres starting pitcher Dylan Cease has compiled an 8-12 (win-loss record), a 4.64 ERA (Earned Run Average) and a 1.32 WHIP (Walks and Hits per Inning Pitched) in 2025. It should also be mentioned that Cease has amassed a massive 207 strikeouts (fifth in MLB) while allowing 69 walks in 163 innings pitched this season.

As I noted in the rules section above, selecting the correct player at the captain position for a Draftkings MLB showdown lineup is absolutely vital if you hope to win a large field GPP (guaranteed prize pool) DFS contest. Keep that in mind as you construct your lineups.

In my opinion, Dylan Cease is the most likely player to post the most Draftkings points in this MLB game. For that specific reason, I am backing San Diego Padres starting pitcher Dylan Cease at the captain position for this one game MLB DFS slate.

Flex plays I like to play well in this MLB regular season contest (Draftkings price noted): Chad Patrick, Starting Pitcher (Milwaukee Brewers) $11,000: Jackson Merrill, Outfielder (San Diego Padres) $7,800.

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