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San Francisco Giants vs San Diego Padres MLB Picks, Odds, Predictions 10/1/21

San Diego Padres (77-81) vs. San Francisco Giants (105-54)
October 1, 2021 9:45 pm EDT
The Line: San Francisco Giants -125 / San Diego Padres -105; Over/Under: +8
(Get latest betting odds)

The San Diego Padres and San Francisco Giants meet Friday in MLB action at Oracle Park. The Padres need a win to snap a six-game losing streak. The Giants look to build on their six-game winning streak. 

The San Diego Padres have scored 13 runs in their last three games and four or more runs in five of their last nine games. The Padres have lost six of their last nine games when scoring four or more runs. Manny Machado leads the Padres with 156 hits and 103 RBI while Jake Cronenworth and Eric Hosmer have combined for 284 hits and 134 RBI. The San Diego Padres didn’t announce a starting pitcher at the time this article was published.

The San Francisco Giants have scored 12 runs in their last three games and four or more runs in eight of their last nine games. The Giants have won eight of their last nine games when scoring four or more runs. Brandon Crawford leads the Giants with 141 hits and 89 RBI while Buster Posey and Mike Yastrzemski have combined for 220 hits and 119 RBI. Anthony DeSclafani gets the ball, and he is 12-7 with a 3.26 ERA and 149 strikeouts this season. DeSclafani is 2-1 with a 2.68 ERA and 33 strikeouts in his career against the Padres.

The Padres are 3-13 in their last 16 during game 1 of a series and 17-35 in their last 52 road games. The Giants are 4-0 in their last 4 Friday games and 40-15 in their last 55 overall. The over is 12-5 in Padres last 17 overall. The under is 4-1 in Giants last 5 overall. The over is 11-1 in the last 12 meetings.

The San Diego Padres continue to fold like a beach chair and it doesn’t matter who they play or who they have on the mound. The San Francisco Giants are a win or two away from wrapping up the NL West and they’ve found ways to win all season long. DeSclafani has also been great all year, which includes 23 hits and eight runs allowed in his last 27 innings. Only one way to go here, and that’s for me to back the Giants.

Randy Chambers's Free Pick: San Francisco Giants -125

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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