Minnesota Twins vs. Chicago White Sox MLB Picks, Odds, Predictions 7/21/2021

The Minnesota Twins and Chicago White Sox meet Wednesday in MLB action at Guaranteed Rate Field. The Twins need a win after losing five of their last six games. The White Sox look for a win after winning four of their last five games.

The Minnesota Twins have scored 11 runs in their last three games and three or less runs in four of their last six games. The Twins have lost three of their last four games when scoring three or less runs. Nelson Cruz leads the Twins with 86 hits and 49 RBI while Jorge Polanco and Luis Arraez have combined for 158 hits and 69 RBI. Michael Pineda gets the ball, and he is 3-5 with a 4.11 ERA and 55 strikeouts this season. Pineda is 5-5 with a 3.78 ERA and 62 strikeouts in his career against the White Sox.

The Chicago White Sox have scored 16 runs in their last three games and four or more runs in four of their last five games. The White Sox have won nine straight games when scoring four or more runs. Tim Anderson leads the White Sox with 103 hits and 36 RBI while Jose Abreu and Yoan Moncada have combined for 167 hits and 119 RBI. Dylan Cease gets the ball, and he is 7-5 with a 4.15 ERA and 127 strikeouts this season. Cease is 1-3 with a 8.04 ERA and 33 strikeouts in his career against the Twins.

The Twins are 1-4 in their last 5 Wednesday games and 2-7 in their last 9 games as an underdog. The White Sox are 4-0 in their last 4 Wednesday games and 45-15 in their last 60 games as a favorite. The under is 5-2 in Twins last 7 road games. The over is 13-5 in White Sox last 18 overall. The Twins are 1-8 in the last 9 meetings in Chicago and 3-12 in the last 15 meetings.

The Twins are going nowhere fast and Pineda has been awful lately, allowing 29 hits and 15 runs in his last 16.2 innings. The White Sox continue to flex their muscle, are now the best team in the AL and Cease has a 2.15 ERA in 50.1 innings at home. This price is way too cheap. Give me the White Sox.