Cleveland Indians vs Chicago White Sox MLB Picks, Odds, Predictions 9/23/21

The Chicago White Sox and Cleveland Indians meet Thursday in a MLB doubleheader at Progressive Field. The White Sox need a win after losing five of their last seven games. The Indians look for a win after splitting their last 10 games.

The Chicago White Sox have scored 13 runs in their last three games and three or less runs in five of their last seven games. The White Sox have lost five straight games when scoring three or less runs. Tim Anderson leads the White Sox with 148 hits and 54 RBI while Jose Abreu and Yoan Moncada have combined for 269 hits and 170 RBI. Reynaldo Lopez and TBD get the ball for the White Sox.

The Cleveland Indians have scored eight runs in their last three games and four or more runs in four of their last eight games. The Indians have won six straight games when scoring four or more runs. Amed Rosario leads the Indians with 144 hits and 51 RBI while Jose Ramirez and Franmil Reyes have combined for 234 hits and 176 RBI. Aaron Civale and Zach Plesac get the ball for the Indians.

The White Sox are 2-5 in their last 7 road games and 2-5 in their last 7 Thursday games. The Indians are 73-35 in their last 108 Thursday games and 1-5 in their last 6 home games. The under is 4-1 in White Sox last 5 overall. The over is 5-2 in Indians last 7 overall. The White Sox are 2-6 in the last 8 meetings in Cleveland.

Game 1 Pick: Lopez has been horrible this month, allowing 16 hits and 10 earned runs in his last 14 innings. Civale has been much more consistent, and he’s allowed just 13 hits and six earned runs in his last 13.2 innings. The Indians should have the edge in the doubleheader opener.

Game 2 Pick: Plesac has been hit or miss all season and he’s allowed 19 hits and 10 earned runs in his last 17 innings. These doubleheaders are also usually split down the middle unless there’s a clear gap between teams. I like the White Sox in the second game.