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Chicago Cubs vs St. Louis Cardinals MLB Picks, Odds, Predictions 9/26/2021

St. Louis Cardinals (86-69) vs. Chicago Cubs (67-88)
September 26, 2021 2:20 pm EDT
The Line: Chicago Cubs +140 / St. Louis Cardinals -161; Over/Under: -
(Get latest betting odds)

The St. Louis Cardinals and the Chicago Cubs meet in an NL Central division matchup in MLB action from Wrigley Field on Sunday afternoon.

The St. Louis Cardinals will look to keep the white hot run going after making it 15 wins in a row with a 6-5 win over Chicago on Saturday. Paul Goldschmidt leads the Cards with a .294 batting average, a .364 OBP and 172 hits while Nolan Arenado has team-highs of 33 home runs and 103 RBIs with both Goldy and Arenado logging 34 doubles. Dylan Carlson has a team-high 4 triples and Tommy Edman has 163 hits with a team-high 41 doubles this season. Jake Woodford will start here and is 3-3 with a 3.92 ERA and 45 strikeouts this season.

The Chicago Cubs will look to bounce back and attempt to snap the streak after another loss on Saturday. Ian Happ leads the Cubs with 100 hits, a .319 OBP and a .227 batting average while Patrick Wisdom has a team-high 28 home runs and Happ leads current Cubs with 63 RBIs this season. Keegan Thompson is expected to make the start here for Chicago and is 3-3 with a 3.40 ERA and 48 strikeouts this season.

St. Louis is 22-6 in their last 28 road games and 21-7 in their last 28 games overall while the over is 4-1 in their last 5 games as a favorite. Chicago is 25-54 in their last 79 games overall and 8-22 in their last 30 home games while the over is 4-1-1 in their last 6 game four matchups.

Simply put, if it isn’t broken, don’t try and fix it. The Cardinals are sitting on 15 straight wins to close the season strong and fire themselves into the wild card spots in the NL and the Cubs, well, they’re showing up to the ballpark. Jake Woodford isn’t the first pitcher I’d think to lay this price on the road with, but sometimes, like I said, you just have to keep riding the hot hand until the tickets stop cashing. Give me St. Louis here.

Chris Ruffolo's Free Pick: St. Louis -161

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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