Pittsburgh Pirates vs Chicago Cubs MLB Picks, Odds, Predictions 9/28/2021

Chicago Cubs (67-89) vs. Pittsburgh Pirates (58-97)
September 28, 2021 6:35 pm EDT
The Line: Pittsburgh Pirates -111 / Chicago Cubs -120; Over/Under: +9
(Click here for latest betting odds)

The Chicago Cubs and the Pittsburgh Pirates meet Tuesday in MLB action from PNC Park. Chicago is coming off a weekend series versus the Cardinals. The Cubs lost all four of those games and have now dropped their last six straight. As for Pittsburgh, they played a one-off game versus the Reds on Monday. In that one the Pirates fell in a blowout loss. Check back all season long for free MLB picks at Sports Chat Place. 

Chicago fell victim to the St. Louis juggernaut over the weekend, falling 8-5 and 12-4 Friday, 8-5 Saturday and 4-2 in the Sunday game. In the finale loss, Cubs pitcher Keegan Thompson finished with 3.0 innings, three hits, one walk and one earned run. 

For the starter gig in the Tuesday game, the Cubs will send out Alec Mills. In 110.0 innings this year Mills has 126 hits, 67 runs (59 earned), 14 homers allowed, 30 walks, 82 Ks and a 4.83 ERA. 

Over on the Pirates’ side, they played the Phillies over the weekend, losing the first three before a win in the Sunday finale. On Monday versus the Reds the Pirates lost 13-1, giving up 17 hits in the process. Connor Overton lasted just 1.0 innings with four earned on six hits.

For the starting pitcher job in the Tuesday opener, the Pirates will send out Mitch Keller. Over his 93.2 innings this year Keller has 119 hits, 62 earned runs, 10 homers allowed, 45 walks, 87 Ks and a 5.96 ERA. 

The Cubs are 25-56 in their last 81 overall and 3-7 in their last 10 after an off day. Chicago is also 1-4 in their last five during game one of a series. 

Meanwhile, the Pirates are 4-1 in their last five Tuesday games and 15-42 in their last 57 versus the NL Central. The under is 6-1 in Pittsburgh’s last seven Tuesday games as well. 

PICK: I’m going to try the Pirates. Keller has been decent over his last two starts (both against the Reds), posting four earned on 11 hits and six walks in a total of 10.2 innings As for Mills, he’s got 10 earned on 12 hits and four walks over his last two starts across 8.2 innings. If Keller is on here, I think Pittsburgh has a good shot at a win. 

Andrew Jett's Free Pick:
Pittsburgh Pirates -111
Free Bet Match Up To $1,001; Use code DAWGZRF

Andrew Jett

Andrew has been writing about college, professional and fantasy sports betting since 2013. Andrew's goal is to break down the complicated numbers and trends into a language that's easily accessible to novice sports bettors and seasoned professionals alike.

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