Chicago White Sox vs Cincinnati Reds MLB Picks, Odds, Predictions 9/29/2021

The Cincinnati Reds and the Chicago White Sox meet Wednesday in MLB action from Guaranteed Rate Field. This will be the second installment in a quick two-game series this week. In the Tuesday opener, Chicago struck first with a blowout win. Check back all season long for free MLB picks at Sports Chat Place. 

Cincinnati played a one-off game versus the Pirates on Monday, cruising to a big 13-1 win. In the Tuesday game versus the Sox, the Reds had a pair of errors during a 7-1 defeat. Riley O’Brien put up 1.1 innings with two earned on two hits and three walks. 

Starting pitcher for the Wednesday game will be Cincinnati’s Sonny Gray. Across his 130.2 innings this year Gray has 110 hits, 62 runs (58 earned), 18 homers allowed, 48 walks, 149 Ks and a 3.99 ERA.

Over on the White Sox’ side, they had their own one-off game Monday, an 8-7 win over the Tigers. On Tuesday, Chicago put up 10 team hits during the big victory. Starter Reynaldo Lopez lasted 6.0 innings with one earned on two hits. 

For the starter gig in the Wednesday game the Sox will send out Carlos Rodon. This year in 23 starts Rodon has a 12-5 record with a 2.47 ERA and 181 Ks in 127.2 innings of work. 

The Reds are 29-62 in their last 91 interleague road games and 17-42 in their last 59 interleague road games versus a lefty starter. Cincinnati is 1-4 in the last five in game two of a series as well. 

Meanwhile, the Sox are 2-7 in their last nine Wednesday games and 0-6 in their last six in game two of a series. Chicago is also 65-31 in their last 96 at home. 

PICK: I’m going with Chicago. Rodon has been solid over his last three outings, posting four earned on 10 hits and three walks in a span of 13.0 innings. As for Gray, he’s got seven earned on nine hits and six walks in 10.0 innings in his last pair. I like Rodon to win the starter battle here and put the White Sox in a good spot for a win.