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Houston Astros vs Boston Red Sox MLB Picks, Odds, Predictions 10/22/2021

Boston Red Sox (98-74) vs. Houston Astros (101-70)
October 22, 2021 8:08 pm EDT
The Line: Houston Astros -130 / Boston Red Sox +110; Over/Under: 8.5
(Get latest betting odds)

The Boston Red Sox and the Houston Astros meet in game six of the ALCS in MLB action from Minute Maid Park on Friday night.

The Boston Red Sox will be out to force a game seven after a 9-1 loss at the hands of the Houston Astros last time out. Rafael Devers had a pair of hits with a solo home run to plate the lone RBI for Boston in the loss while Christian Vazquez had a double as the Red Sox mustered up just three hits as a team in the losing effort. Chris Sale took the loss, allowing two earned runs on three hits while striking out seven over 5.1 innings of work. Nathan Eovaldi will start this one and is 2-1 with a 5.51 ERA and 21 strikeouts this postseason.

The Houston Astros will be out to close out the series after taking game five last time out. Yordan Alvarez and Yuli Gurriel each went 3 for 5 with a double and three RBIs with Alvarez hitting a solo homer as well. Jose Siri had two RBIs and Michael Brantley added an RBI as well to cap off Houston’s scoring as a team in the win. Jose Altuve and Kyle Tucker each had a base hit as well to round out the offense. Framber Valdez got the win with eight strong innings, allowing just one run on three hits with five strikeouts. Luis Garcia will start here and is 0-1 with a 24.55 ERA and 5 strikeouts this postseason.

Boston is 14-5 in their last 19 playoff games and 4-1 in their last 5 games following a loss while the over is 10-1-1 in their last 12 games against the AL West. Houston is 8-3 in their last 11 games overall and 5-2 in their last 7 games following a win while the over is 8-0 in their last 8 playoff games.

This is an interesting matchup with so much at stake for both teams however, both of these pitchers have been torched earlier in the series and the over has been hitting like nobody’s business over the course of this series and even with so much on the line in game six, I still have to side with the over once again.

Chris Ruffolo's Free Pick: Over 8.5

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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