Angels vs Brewers Prediction 9/17/25 MLB Picks Today

In this article, we will formulate an Angels vs Brewers Prediction for this MLB game on Wednesday, September 17th at the American Family Field in the second game of this series, with the Brewers having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Milwaukee Brewers Preview

The Milwaukee Brewers have a 92-59 record this season and are sitting on the first place of the NL Central. They have a 49-27 home record and are 73-73 in over/under. They are coming off a 9-2 home victory over the Angels, and are 3-1 in their last 4 games. Over is 6-2 in their last 8 games and are playing the Cardinals and the Padres next.

The Brewers have a .261 batting average this season, .334 OBP and .409 Slugging percentage. Milwaukee’s pitching staff has a 3.62 ERA and 1.23 WHIP. Brice Turang leads the Brewers with 157 hits, while Christian Yelich leads the team in RBI, with 99, adding a team-high 29 home runs. Sal Frelick is the team’s best hitter with a .296 batting average.

Brandon Woodruff (R) is the projected starting pitcher for the Brewers, and he has a 6-2 record, 3.32 ERA and 0.96 WHIP.

Los Angeles Angels Preview

The Los Angeles Angels have a 69-82 record this season and are sitting on the 4th place of the AL West. The Angels have a 32-44 road record and 83-65 in over/under They are coming off a 2-9 road defeat by the Mariners, and have five consecutive losses. Over is 8-3 in their last 11 games and are playing the Rockies and the Royals next.

The Angels have a .227 batting average this season, .301 OBP and .399 Slugging percentage. LA’s pitching staff has a 4.86 ERA and 1.44 WHIP. Zach Neto leads the Angels with 129 hits, while Nolan Schanuel is the team’s best hitter with a .266 batting average. Taylor Ward leads the team with 98 RBI, while Jo Adell adds a team-high 36 home runs.

Jose Soriano (R) is the projected starting pitcher for the Angels, and he has a 10-10 record, 4.13 ERA and 1.38 WHIP.

Los Angeles Angels @ Milwaukee Brewers Betting Trends: September 17, 2025

 

Why the Milwaukee Brewers will win

 

Why the Los Angeles Angels will win

Total Runs Facts

Milwaukee Brewers Player Prop Facts

Los Angeles Angels Player Prop Facts

Matchup/League Facts

Angels vs Brewers Prediction

The Brewers are 5-2 in their last 7 meetings against the Angels, and are 3-2 in their last 5 meetings Milwaukee. Under is 5-2-1 in their last 8 meetings.

In this Angels vs Brewers Prediction, the Brewers are coming as -200 home favorites. The Brewers have once again the pitching advantage in this matchup, as Brandon Woodruff takes the mound, and he has been elite this season, coming off a shutout start against the Pirates. On the flip side, Soriano has given up 11 runs in his last two starts for the Angels, who also have the third-worst bullpen in baseball. Milwaukee has the third-best offense in the league, and I expect them to dominate this game once again and cover the runline.

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