Arizona Diamondbacks vs Colorado Rockies Prediction 5/22/26 MLB Picks Today

The Colorado Rockies and the Arizona Diamondbacks meet Friday in MLB action from Chase Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Colorado Rockies vs. Arizona Diamondbacks prediction.

Starting Pitching Matchup

The Colorado Rockies will send out Tomoyuki Sugano for the start here and Sugano is 4-3 with a 4.02 ERA and 25 strikeouts this season. This will be Sugano’s second career start against Arizona. Michael Soroka will start here for the Diamondbacks and is 6-2 with a 3.49 ERA and 55 strikeouts this season. In his career, Soroka is 1-1 with a 3.86 ERA and 17 strikeouts against the Rockies.

Colorado Rockies Recap

The Colorado Rockies come into this game looking to bounce back from a 2-1 loss at the hands of the Diamondbacks in Thursday’s series opener to sit at 19-22 this season. After this series, the Rockies will head on the road for a series against the Los Angeles Dodgers.

Rockies Lose 3 In A Row

TJ Rumfield has 50 hits with 8 doubles, a triple, 6 home runs and 25 RBIs while Ezequiel Tovar has 34 hits with 11 doubles, a home run and 13 RBIs. Hunter Goodman’s added 41 hits with 8 doubles, 11 home runs and 19 RBIs and Jordan Beck has 10 RBIs as well on the year. Troy Johnston has 48 hits with 13 doubles, 2 home runs and 22 RBIs. Willi Castro also has 33 hits with 8 doubles, 2 home runs and 16 RBIs.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to add on to their series opening win over Colorado last time out to sit at 26-23 this season. After this series, the Diamondbacks will head on the road for a series against the San Francisco Giants.

Diamondbacks Win 5 In A Row

Corbin Carroll has 46 hits including 11 doubles, 6 triples, 7 home runs and 26 RBIs while Alek Thomas has logged 9 doubles with 2 home runs and 10 RBIs as well this season. Ketel Marte has 44 hits with 7 doubles, 7 home runs and 22 RBIs and Geraldo Perdomo has 35 hits, with 8 doubles, 3 triples, 2 home runs and 15 RBIs as well this season. Nolan Arenado also has 42 hits with 9 doubles, 7 home runs and 25 RBIs and Jose Fernandez has 36 hits with 3 home runs and 14 RBIs this season. Ildemaro Vargas also has 55 hits with 8 doubles, 2 triples, 7 home runs and 32 RBIs.

Colorado Rockies @ Arizona Diamondbacks Betting Trends: May 22, 2026

 

Why the Arizona Diamondbacks will win

 

Why the Colorado Rockies will win

Total Runs Facts

Arizona Diamondbacks Player Prop Facts

Colorado Rockies Player Prop Facts

Matchup/League Facts

Colorado Rockies vs. Arizona Diamondbacks Prediction

I’m on the Diamondbacks here. The Rockies’ struggles on the road have been well documented over the years and I don’t really expect that to change here against Soroka who just stifled the Rockies in his last start against them. Sugano won his last start against Arizona in fairness, but I trust Arizona’s bats to replicate their success here more than I do Colorado’s. Give me the Diamondbacks.

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