Arizona Diamondbacks vs. Boston Red Sox Prediction 5-27-23 MLB Picks

Chris RuffoloMay 27, 2023
Arizona Diamondbacks vs. Boston Red Sox Prediction 5-27-23 MLB Picks player photo
Credit: USA Today Sports

The Boston Red Sox and the Arizona Diamondbacks meet in an interleague matchup in MLB action from Chase Field on Saturday. Let’s dive into the odds, starting pitching matchup, history and make a prediction for this game.


Boston is listed as a -135 road favorite while Arizona is a +115 home underdog. The total for this game is set at 9.5 runs.

Starting Pitching Matchup

Garrett Whitlock will start for Boston on Saturday and is 1-2 with a 6.19 ERA and 11 strikeouts this season. Zach Davies will start for Arizona and is 0-0 with a 5.79 ERA and 7 strikeouts this season.

Matchup History

Boston’s 7-2 win on Friday was their first over Arizona since these two teams met back in 2019.


Boston is 1-4 in their last 5 games overall and 58-26 in their last 84 games against the NL West while the over is 10-2 in their last 12 Saturday games. Arizona is 13-4 in their last 17 games against a team with a winning record and 9-4 in their last 13 interleague games while the over is 4-1 in their last 5 games against a team with a winning record.


I’m backing the over here. I don’t trust this pitching matchup as far as I can throw it, as Whitlock’s been hard to trust on the mound, resulting in his flopping back and forth from the starting rotation to the bullpen, and Zach Davies also hasn’t been a pitcher I’ve been able to trust or rely on over the course of his major league career. All in all, I think this ends up being a higher-scoring game and as such, I’m backing the over.  

Chris Ruffolo's Free Pick:Over 9.5
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Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg