Astros vs Blue Jays Prediction 4/21/25 MLB Picks Today

The Toronto Blue Jays and Houston Astros meet Monday in MLB action at Daikin Park. Here’s an Astros vs Blue Jays Prediction. This article will include an Astros vs Blue Jays Pick.

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 12-10 on the year and play the Yankees, Red Sox, and Guardians next. The Toronto Blue Jays are batting .259 on the season, have a .333 OBP, and a .368 slugging percentage. The Toronto Blue Jays’ pitching staff has a 3.58 ERA and a 1.11 WHIP. Bo Bichette leads the Toronto Blue Jays with 30 hits and 13 RBI, while Vladimir Guerrero Jr. and George Springer have combined for 46 hits and 21 RBI.


Kevin Gausman gets the ball for the Toronto Blue Jays, and he is 2-1 with a 2.49 ERA and 20 strikeouts this season. Gausman is 3-4 with a 5.01 ERA and 54 strikeouts in his career against the Houston Astros.

Houston Astros Betting Preview

The Houston Astros are 10-11 on the year and play the Royals, Tigers, and White Sox next. The Houston Astros are batting .222 on the season, have a .299 OBP, and a .331 slugging percentage. The Houston Astros’ pitching staff has a 3.63 ERA and a 1.16 WHIP. Jose Altuve leads the Houston Astros with 26 hits and 7 RBI, while Jake Meyers and Isaac Paredes have combined for 36 hits and 16 RBI.

Hunter Brown gets the ball for the Houston Astros, and he is 2-1 with a 1.50 ERA and 22 strikeouts this season. Brown is 1-1 with a 2.45 ERA and 10 strikeouts in his career against the Toronto Blue Jays.

Why the Houston Astros will win

Why the Toronto Blue Jays will win

Houston Astros Player Prop Facts

Toronto Blue Jays Player Prop Facts

Astros vs Blue Jays Prediction

We’re getting plus money with the Blue Jays, the team that has had more success swinging the plate this season. The pitching matchup is a bit of a wash as Brown and Gausman have both been solid up to this point. Gausman has allowed 15 hits and seven earned runs in 25.1 innings, while Brown has allowed 15 hits and four earned runs in 24 innings. The difference is that the Blue Jays have been more consistent offensively.

The Astros have yet to find their form offensively, and I don’t believe that starts against a veteran in good form in Gausman. I’ll take a shot at the more favorable price on Monday night.

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