Astros vs Cardinals Prediction 4/19/26 MLB Picks Today

In this article we will formulate an Astros vs Cardinals prediction for this MLB game on Sunday, April 19th at Daikin Park in Houston, Texas. Let’s take a look at the prediction for this MLB matchup. 

Houston Astros Betting Preview

The Houston Astros are 8-14 this year after they lost the first two games in this series by scores of 4-9 and 5-7. In game two, Houston cut the deficit to 2-1 in the first inning, but they didn’t score again until the eighth in the loss. The Astros recorded four hits and they committed two errors in the game, while they were led by Whitcomb, who went 1-4 with one home run and three RBIs. McCullers Jr allowed four hits and four earned runs over 5.0 innings for the loss, while Gordon allowed three earned runs in relief. Prior to this series, Houston won two out of three against the Rockies, but lost all four against the Mariners before that. 

This season, Houston has a 6.19 ERA with a 1.65 WHIP and a .266 opponent batting average, while they have scored 116 runs with a .257 batting average and a .352 on base percentage. Yordan Alvarez has led the Astros with nine home runs and 20 RBIs, while Christian Walker has added four home runs and 16 RBIs. The projected starting pitcher for Houston is Mike Burrows, who is 1-3 with a 6.55 ERA and a 1.82 WHIP over 22.0 innings pitched this year. 

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 12-8 this season after they won game two by a score of 7-5 on Saturday night. St. Louis scored two runs in the first inning and they added two more in the third + one more in the sixth to pull away for the win. The Cardinals recorded nine hits in the game and they were led by Gorman and Winn, who both had two RBIs. Pallante allowed three hits and one earned run over 5.0 innings for the win, while O’Brien picked up the save. Prior to this series, St. Louis won two out of three against the Guardians, but lost two out of three against the Red Sox before that. 

This season, St. Louis has a 4.90 ERA with a 1.43 WHIP and a .256 opponent batting average, while they have scored 96 runs with a .234 batting average and a .330 on base percentage. Jordan Walker has led the Cardinals with eight home runs and 16 RBIs, while Alec Burleson has added three home runs and 15 RBIs. The projected starting pitcher for St. Louis is Matthew Liberatore, who is 0-1 with a 4.29 ERA and a 1.57 WHIP over 21.0 innings pitched this season. 

Why the Houston Astros will win

Why the St. Louis Cardinals will win

Total Runs Facts

Houston Astros Player Prop Facts

St. Louis Cardinals Player Prop Facts

Astros vs Cardinals Prediction 

Houston comes into this matchup on a three game losing streak and they have allowed 16 runs in the first two games of this series. The Astros are 7-5 at home this year, while the Cardinals are 5-3 on the road. St. Louis has won four games in a row and they have scored 5+ runs in all four wins. The Cardinals are starting Liberatore, who has allowed eight earned runs and 15 hits over his last 10.0 innings, while Burrows has allowed 6, 3, 2, and 5 earned runs in his first four starts. I think we are going to see plenty of scoring in this one, but I like the Cardinals, as this Houston pitching staff continues to be a disaster. 

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