Astros vs Mariners Prediction 4/10/26 MLB Picks Today

In this article, we will formulate an Astros vs Mariners Prediction for this MLB matchup on Friday, April 10th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Seattle Mariners Preview

The Seattle Mariners have a 4-9 record this season and are sitting in the fifth place of the AL West. They have a 3-4 home record and are coming off a 0-3 road loss against the Rangers. Their previous three games were a 2-3 and a 1-2 road loss to the Rangers, and a 7-8 road loss to the Angels.


The Mariners have a .184 batting average this season, .280 OBP and .301 Slugging percentage. Seattle’s pitching staff has a 2.62 ERA and 0.95 WHIP. Brendan Donovan is the team’s best hitter with a .316 batting average. Cole Young leads the team in RBI with 8, and Luke Raley adds a team-high 3 home runs.

Emerson Hancock (R) is the projected starting pitcher for the Mariners, and he has a 1-1 record, 0.71 ERA and 0.55 WHIP.

Houston Astros Preview

The Houston Astros have a 6-7 record this season and are sitting in the second place of the AL West. They have a 1-5 away record and are coming off a 1-9 road loss against the Rockies. Their previous three games were a 1-5 and a 7-9 road loss to the Rockies, and a 10-12 road loss to the Athletics.

The Astros have a .271 batting average this season, .371 OBP and .453 Slugging percentage. Houston’s pitching staff has a 6.05 ERA and 1.63 WHIP. Christian Walker is the team’s best hitter with a .340 batting average, also leading the team in RBI with 13. Yordan Alvarez adds a team-high 4 home runs.

Tatsuya Imai (R) is the projected starting pitcher for the Astros, and he has a 1-0 record, 4.32 ERA and 1.56 WHIP.

Houston Astros @ Seattle Mariners Betting Trends: April 10, 2026

 

Why the Seattle Mariners will win

 

Why the Houston Astros will win

Total Runs Facts

Seattle Mariners Player Prop Facts

Houston Astros Player Prop Facts

Matchup/League Facts

Astros vs Mariners Prediction

The Mariners are 5-1 in their last 6 meetings against the Astros and the over is 4-1 in their last 5 meetings.

In this Astros vs Mariners Prediction, the Mariners are coming as -140 home favorites. Both teams have been struggling early this season as they have lost their last five and four games respectively. The Mariners have the pitching edge in this one, as Hancock goes up against Tatsuya Imai, with Hancock having just one earned run in two starts. Imai is coming off a shutout start and the Astros have scored just 2 total runs in their last two games. The Mariners have the third-best bullpen in baseball and are 7-2 to the under in their last 9 games, barely averaging 3+ runs this season, so this sets up for a low-scoring affair. Take the under 7.5 in this one.

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