Astros vs White Sox Prediction 6/11/25 MLB Picks Today

The Chicago White Sox and Houston Astros meet Wednesday in MLB action at Daikin Park. Here’s an Astros vs White Sox Prediction. This article will include an Astros vs White Sox Pick.

Chicago White Sox Betting Preview

The Chicago White Sox are 23-44 on the year and play the Rangers, Cardinals, and Blue Jays next. The Chicago White Sox are batting .222 on the season, have a .297 OBP, and a .344 slugging percentage. The Chicago White Sox pitching staff has a 4.09 ERA and a 1.37 WHIP. Lenyn Sosa leads the Chicago White Sox with 55 hits and 17 RBI, while Miguel Vargas and Chase Meidroth have combined for 100 hits and 38 RBI.

Sean Burke gets the ball for the Chicago White Sox, and he is 3-6 with a 4.03 ERA and 50 strikeouts this season. This will be Burke’s first career game against the Houston Astros.

Houston Astros Betting Preview

The Houston Astros are 36-30 on the year and play the Twins, Athletics, and Angels next. The Houston Astros are batting .251 on the season, have a .16 OBP, and a .385 slugging percentage. The Houston Astros’ pitching staff has a 3.53 ERA and a 1.17 WHIP. Jeremy Pena leads the Houston Astros with 81 hits and 32 RBI, while Jose Altuve and Jake Meyers have combined for 127 hits and 40 RBI.

Ryan Gusto gets the ball for the Houston Astros, and he is 3-3 with a 4.78 ERA and 45 strikeouts this season. This will be Gusto’s second career game against the Chicago White Sox.

Why the Houston Astros will win

Why the Chicago White Sox will win

Houston Astros Player Prop Facts

Chicago White Sox Player Prop Facts

Astros vs White Sox Prediction

The Astros should be favored for obvious reasons, and the White Sox are a team I’ve faded blindly over the years. However, this price is steep for Gusto, who has allowed 25 hits and 14 earned runs in his last 16.1 innings. The Astros have lost each of the last six games Gusto has pitched. The White Sox have quietly won games over the last week, and Burke has been sharp lately, allowing 32 hits and 12 earned runs in his last 40 innings. I don’t back the White Sox often, but this is a spot where there’s value. I’ll take a shot in the dark.

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