Athletics vs Cardinals Prediction 9/1/25 MLB Picks Today

In this article, we will formulate an Athletics vs Cardinals Prediction for this MLB game on Monday, September 1st at the Busch Stadium in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Saint Louis Cardinals Preview

The Saint Louis Cardinals have a 68-70 record this season and are sitting on the 4th place of the NL Central. The Cardinals have a 37-32 home record and are 70-60 in over/under. They are coming off a 4-7 road defeat by the Reds, that ended their three-game winning streak. Over is 6-3-1 in their last 10 games and are playing the Giants and the Mariners next.

The Cardinals have a .247 batting average this season, .316 OBP and .384 Slugging percentage. Saint Louis’ pitching staff has a 4.27 ERA and 1.31 WHIP. Alec Burleson leads the Cardinals with 123 hits, and he is the team’s best hitter with a .286 batting average. Wilson Contreras leads the team in RBI, with 74, adding a team-high 20 home runs.

Sonny Gray (R) is the projected starting pitcher for the Cardinals, and he has a 12-7 record, 4.19 ERA and 1.18 WHIP.

Athletics Preview

The Athletics have a 63-75 record this season and are sitting on the last place of the AL West. The Athletics have a 34-35 road record and are 70-62 in over/under. They are coming off a 6-9 home defeat by the Rangers, and have three consecutive losses. Over is 5-2 in their last 7 games and are playing the Red Sox and the Angels next.

The Athletics have a .253 batting average this season, .318 OBP and .431 Slugging percentage. Athleticspitching staff has a 4.83 ERA and 1.37 WHIP. Brent Rooker leads the Athletics with 145 hits, while Jacob Wilson is the team’s best hitter with a .313 batting average. Brent Rooker also adds a team-high 79 RBI, while Shea Langeliers adds a team-high 29 home runs.

Luis Morales (R) is the projected starter for the Athletics, and he has a 2-0 record, 1.19 ERA, and 0.97 WHIP.

Why the St. Louis Cardinals will win

Why the Athletics will win

Total Runs Facts

Matchup/League Facts

Athletics vs Cardinals Prediction

The Cardinals are 4-2 in their last 6 head-to-head meetings against the Athletics, but the Athletics have won their four meetings before that, and both teams are tied 2-2 wins in their last 4 meetings in Saint Louis. Under is 4-1 in their last 5 meetings.

In this Athletics vs Cardinals Prediction, the Cardinals are coming as -140 home favorites. Morales has been almost unhittable for the A’s, as he has only two earned runs in 20.2 innings pitched in his four starts this season. On the flip side, Gray has been excellent this season and even better at home, with a 3.57 home ERA. I don’t trust either offense to do damage against those two pitchers, and on top of that, the Cardinals have the 6th-best bullpen ERA in the league. I expect runs to come at a premium in this matchup, so take the under 8 runs.

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