Baltimore Orioles vs Boston Red Sox Prediction 4/25/26 MLB Picks Today

The Boston Red Sox and the Baltimore Orioles meet Saturday in MLB action from Camden Yards. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Boston Red Sox vs. Baltimore Orioles prediction.

Starting Pitching Matchup

The Boston Red Sox will start Garrett Crochet here and Crochet is 2-3 with a 7.88 ERA and 30 strikeouts this season. In his career, Crochet is 1-1 with a 1.80 ERA and 26 strikeouts against Baltimore. The Baltimore Orioles will send Trevor Rogers out for the start here and Rogers is 2-2 with a 4.08 ERA and 25 strikeouts this season. In his last five starts against the Red Sox, Rogers is 1-2 with a 2.13 ERA and 27 strikeouts.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to bounce back from a 10-3 loss at the hands of Baltimore last time out to sit at 9-17 this season. After this series, the Red Sox will head on the road for a series against the Toronto Blue Jays.

Red Sox Drop 6 Of Last 7

Entering Friday, Wilyer Abreu leads the Red Sox with 26 hits including 4 doubles, a triple, 3 home runs and 11 RBIs while Trevor Story has 19 hits with 5 doubles, 2 homers and 17 RBIs and Marcelo Mayer’s added 12 hits with 5 doubles, a home run and 4 RBIs as well. Roman Anthony has 18 hits with 3 doubles, a triple, a home run and 4 RBIs so far this season while Jarren Duran has 15 hits with 5 doubles, a home run and 11 RBIs as well this season. Willson Contreras has added 21 hits with 2 doubles, 4 homers and 12 RBIs of his own on the year.

Baltimore Orioles Recap

The Baltimore Orioles come into this game looking to build on their win over Boston from Friday’s matchup to sit at 13-13 on the year. After this series, the Orioles will take on the Houston Astros in a series at home.

Orioles Pick Up Back-To-Back Ws

Going into Friday, Taylor Ward has 28 hits with 13 doubles and 11 RBIs while Gunnar Henderson has 20 hits with 4 doubles, 7 home runs and 15 RBIs and Pete Alonso has 20 hits with 6 doubles, 3 home runs and 10 RBIs. Adley Rutschman has 12 hits with 6 doubles and 5 RBIs. Jeremiah Jackson has 23 hits with 2 doubles, 5 home runs and 19 RBIs while Dylan Beavers also has 14 hits with 3 doubles, a home run and 7 RBIs.

Boston Red Sox @ Baltimore Orioles Betting Trends: April 25, 2026

 

Why the Baltimore Orioles will win

 

Why the Boston Red Sox will win

Total Runs Facts

Baltimore Orioles Player Prop Facts

Boston Red Sox Player Prop Facts

Matchup/League Facts

Boston Red Sox vs. Baltimore Orioles Prediction

I’m on the Orioles here. I know Crochet is supposed to be Boston’s staff ace, but he hasn’t pitched like it for much of the year, and I think this is a situation where Baltiimore can get to him as many teams already have this season. Trevor Rogers hasn’t been sharp as of late either, but he was really solid at Camden Yards last season and I think being at home is more of a benefit for him here. Give me the Orioles.

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