Blue Jays vs Cubs Prediction 6/21/26 MLB Picks Today

In this article, we will formulate a Blue Jays vs Cubs Prediction for this MLB matchup on Sunday, June 21st in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago Cubs Preview

The Chicago Cubs have a 40-37 record this season and are sitting in the 3rd place of the NL Central. They have a 23-17 home record and are coming off a 6-8 home defeat against the Blue Jays. They will face the Mets and the Brewers next.

The Cubs have a .244 batting average this season, .337 OBP and .401 Slugging percentage. Chicago’s pitching staff has a 4.28 ERA and 1.24 WHIP. Pete Crow-Armstrong is the team’s best hitter with a .286 batting average. Michael Busch leads the team in RBI with 42, while Ian Happ adds a team-high 16 home runs.

Shota Imanaga (L) is the projected starting pitcher for the Cubs, and he has a 4-6 record, 4.26 ERA and 1.06 WHIP.

Toronto Blue Jays Preview

The Toronto Blue Jays have a 38-39 record this season and are sitting in the 3rd place of the AL East. They have a 17-21 road record and are coming off an 8-6 road win against the Cubs. They will face the Astros and the Rangers next.

The Blue Jays have a .249 batting average this season, .311 OBP and .391 Slugging percentage. Toronto’s pitching staff has a 4.13 ERA and 1.31 WHIP. Ernie Clement is the team’s best hitter with a .292 batting average. Kazuma Okamoto leads the team in RBI with 45, adding a team-high 16 home runs.

Dylan Cease (R) is the projected starting pitcher for the Blue Jays, and he has a 4-3 record, 2.71 ERA and 1.19 WHIP.

Toronto Blue Jays @ the Chicago Cubs Betting Trends: June 21, 2026

 

Why the Chicago Cubs will win

 

Why the Toronto Blue Jays will win

Total Runs Facts

Chicago Cubs Player Prop Facts

Toronto Blue Jays Player Prop Facts

Matchup/League Facts

Blue Jays vs Cubs Prediction

The Jays are 4-2 in their last 6 meetings against the Cubs and have won two of their last three visits in Chicago.

In this Blue Jays vs Cubs Prediction, the Blue Jays are coming as -130 road favorites. The Jays are being favorited in Chicago even though they lost in the opening game of this series by 2-16 and are facing a leftie in Imanaga. I will gladly take the plus money with the home team, as Imanaga has bounced back and has one earned run in his last two starts, the Cubs have a slightly better bullpen and a superior offense, with the Jays being weaker against southpaws. Take the Cubs to win.

 

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