Boston Red Sox vs Detroit Tigers Prediction 4/18/26 MLB Picks Today

The Detroit Tigers and the Boston Red Sox meet Wednesday in MLB action from Fenway Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Detroit Tigers vs. Boston Red Sox prediction.

Starting Pitching Matchup

The Detroit Tigers will send out Tarik Skubal for the start here and Skubal is 2-2 with a 2.22 ERA and 23 strikeouts this season. In his last five starts against the Red Sox, Skubal is 2-2 with a 4.91 ERA and 31 strikeouts. Brayan Bello will start for Boston here and is 1-1 with a 6.14 ERA and 9 strikeouts this season. In his career, Bello is 0-1 with a 5.74 ERA and 14 strikeouts against Detroit.

Detroit Tigers Recap

The Detroit Tigers come into this game looking to bounce back from a 1-0 loss at the hands of Boston in Friday’s matchup to sit at 10-10 this season. After this series, Detroit will head home for a series against the Milwaukee Brewers.

Tigers Have Six-Game Win Streak Snapped

Colt Keith has 19 hits with 7 doubles and 5 RBIs while Kevin McGonigle’s added 22 hits with 6 doubles, 2 triples, a home run and 8 RBIs this season. Riley Greene has chipped in 18 hits with 6 doubles, a home run and 12 RBIs and Dillon Dingler’s added 15 hits with 3 doubles, 4 home runs and 14 RBIs. Kerry Carpenter also has 3 home runs and 10 RBIs so far this season.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to add on to their win over Detroit from Friday’s opener to sit at 8-11 this season. After this series, the Red Sox will renew their rivalry series against the New York Yankees.

Red Sox Win 6 Of Last 9

Wilyer Abreu leads the Red Sox with 22 hits including 4 doubles, a triple, 3 home runs and 10 RBIs while Trevor Story has 16 hits with 4 doubles, 2 homers and 17 RBIs and Marcelo Mayer’s added 9 hits with 3 doubles, a home run and 3 RBIs as well. Roman Anthony has 16 hits with 3 doubles, a triple, a home run and 3 RBIs so far this season while Jarren Duran has 11 hits with 3 doubles, a home run and 10 RBIs as well this season. Willson Contreras has added 17 hits with 2 doubles, 3 homers and 11 RBIs of his own on the year.

Detroit Tigers @ Boston Red Sox Betting Trends: April 18, 2026

 

Why the Boston Red Sox will win

 

Why the Detroit Tigers will win

Total Runs Facts

Boston Red Sox Player Prop Facts

Detroit Tigers Player Prop Facts

Matchup/League Facts

Detroit Tigers vs. Boston Red Sox Prediction

I’m on the over in this game. The Detroit Tigers have a favorable matchup against Brayan Bello, who has been hittable at Fenway Park for the better part of his career. However, Tarik Skubal’s worst start last year came against these Red Sox and I think they can get to him for a few runs here to end up with a much higher-scoring game than Friday’s opener. Give me the over in this one.

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