The New York Yankees and the Boston Red Sox meet Wednesday in MLB action from Fenway Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a New York Yankees vs. Boston Red Sox prediction.
Starting Pitching Matchup
The New York Yankees will send out Max Fried for the start here and Fried is 2-1 with a 2.97 ERA and 23 strikeouts this season. Ranger Suarez will start for the Phillies here and is 1-1 with a 3.22 ERA and 15 strikeouts this season.
New York Yankees Recap
The New York Yankees come into this game looking to add on to their 4-0 win over the Red Sox from Tuesday’s opener to sit at 14-9 this season. After this series, the Yankees will head on the road again for a series against the Houston Astros.
Yankees Win 4 In A Row
Going into Tuesday, Giancarlo Stanton has 18 hits with 3 doubles, 2 home runs and 10 RBIs while Ben Rice has 22 hits with 6 doubles, 8 home runs and 18 RBIs and Aaron Judge has 19 hits with 3 doubles, 9 home runs and 16 RBIs. Cody Bellinger also has 21 hits with 3 doubles, a triple, 3 home runs and 11 RBIs. Jazz Chisholm Jr. also has 12 hits with 5 doubles as well on the year.
Boston Red Sox Recap
The Boston Red Sox come into this game looking to bounce back from their loss at the hands of the Yankees from Tuesday’s opener to fall to 9-14 this season. After this series, the Red Sox will head on the road for a series against the Baltimore Orioles.
Red Sox Drop 3 Of Last 4
Entering Tuesday, Wilyer Abreu leads the Red Sox with 24 hits including 4 doubles, a triple, 3 home runs and 11 RBIs while Trevor Story has 18 hits with 5 doubles, 2 homers and 17 RBIs and Marcelo Mayer’s added 10 hits with 3 doubles, a home run and 3 RBIs as well. Roman Anthony has 18 hits with 3 doubles, a triple, a home run and 4 RBIs so far this season while Jarren Duran has 11 hits with 3 doubles, a home run and 10 RBIs as well this season. Willson Contreras has added 20 hits with 2 doubles, 4 homers and 12 RBIs of his own on the year.
New York Yankees @ Boston Red Sox Betting Trends: April 22, 2026
- Probable Starting Pitcher: Ranger Suarez Record this season: 1-1 ERA: 3.22
- Home Record: 0-0
- Last 5 against Yankees: 1-1
Why the Boston Red Sox will win
- The Yankees have lost each of their last four games as favorites against AL East opponents.
- The Red Sox have won eight of their last 12 games as home underdogs after playing the previous day.
- The Yankees have failed to cover the run line in each of their last seven Wednesday games as favorites against AL East opponents.
- The Red Sox have covered the run line in each of their last three night games against AL East opponents following a home loss.
- The Red Sox have led after 3 innings in seven of their last eight Wednesday home games.
- The Yankees have trailed after 5 innings in four of their last five games as road favorites against AL East opponents.
- Probable Starting Pitcher: Max Fried Record this season: 2-1 ERA: 2.97
- Road Record: 2-0
- Last 5 against Red Sox: 2-1
Why the New York Yankees will win
- The Yankees have won each of their last 11 Wednesday games against the Red Sox.
- The Red Sox have lost seven of their last eight night games against American League opponents.
- The Red Sox have failed to cover the run line in each of their last seven night games against American League opponents.
- The Yankees have covered the run line in each of their last four games.
- The Yankees have led after 3 innings in five of their last six games.
- The Red Sox have lost the first inning in each of their last three games as home underdogs against American League opponents.
- The Red Sox have trailed after 5 innings in nine of their last 10 night games against American League opponents.
Total Runs Facts
- Seven of the Red Sox’s last eight games as underdogs against AL East opponents have gone UNDER the total runs line.
- Each of the Yankees’ last five games as favorites against the Red Sox have gone UNDER the total runs line.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Red Sox’s last 10 Wednesday games against American League opponents.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in 14 of the Yankees’ last 16 games at Fenway Park.
Boston Red Sox Player Prop Facts
- Wilyer Abreu has hit a home run in each of his last two appearances with the Red Sox as home underdogs against AL East opponents.
- Ranger Suarez has recorded a win in three of his last four appearances with his team as an underdog .
- Ranger Suarez has recorded six or more strikeouts in each of his last five appearances against AL East opponents that held a winning record.
- Jarren Duran has recorded at least one hit in each of his last 23 Wednesday appearances at Fenway Park.
New York Yankees Player Prop Facts
- Aaron Judge has hit at least one home run in five of the Yankees’ last eight games as favorites.
- Max Fried has recorded a win in six of his last seven road appearances against opponents that held a losing record.
- Max Fried has recorded six or more strikeouts in each of his last 13 appearances in night games against teams that held a losing record.
- Cody Bellinger has recorded at least one hit in each of his last nine appearances.
- Ben Rice ranks 1st amongst qualified players for Slugging Percentage (.754) this season.
Matchup/League Facts
- The Red Sox rank T29th in the league for home runs this season (13).
- The Red Sox rank 29th in the league for slugging percentage this season (.338).
- The Yankees rank 2nd in the league for steals this season (27).
- The Yankees rank 2nd in the league for walks this season (113).
New York Yankees vs. Boston Red Sox Prediction
I’m on the under in this one. We have quite the starting pitching matchup here with Fried vs. Suarez, as I think Fried can have a solid outing to bounce back from a rough one last time out, while I think Suarez has a good showing against a Yankees team that’s struggled against lefties on the road this season. Give me the under in this one.