Brewers vs Cubs Prediction 10/6/25 MLB Picks Today

The Chicago Cubs and Milwaukee Brewers meet Monday in Game 2 NLDS MLB action at American Family Field. Here’s a Brewers vs Cubs Prediction. This article will include a Brewers vs Cubs Pick.

Chicago Cubs Betting Preview

The Chicago Cubs need a bounce back effort to even up the series at 1-1. The Chicago Cubs are batting .238 on the season, have a .282 OBP, and a .426 slugging percentage. The Chicago Cubs pitching staff has a 2.57 ERA and a 1.17 WHIP. Nico Hoerner leads the Chicago Cubs with 5 hits and 2 RBI, while Michael Busch and Pete Crow-Armstrong have combined for 9 hits and 3 RBI.

Shota Imanaga gets the ball for the Chicago Cubs, and he is 9-8 with a 3.73 ERA and 117 strikeouts this season. Imanaga is 0-0 with a 4.50 ERA and 3 strikeouts in his postseason career. Imanaga is 1-3 with a 5.73 ERA and 18 strikeouts in his career against the Milwaukee Brewers.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers look for another win to take a quick 2-0 series lead. The Milwaukee Brewers are batting .351 on the season, have a .429 OBP, and a .459 slugging percentage. The Milwaukee Brewers pitching staff has a 3.00 ERA and a 1.00 WHIP. Jackson Chourio leads the Milwaukee Brewers with 3 hits and 3 RBI while Blake Perkins and William Contreras have combined for 4 hits and 2 RBI.

Aaron Ashby gets the ball for the Milwaukee Brewers, and he is 5-2 with a 2.16 ERA and 76 strikeouts this season. Ashby is 0-0 with a 9.00 ERA and 4 strikeouts in his postseason career. Ashby is 2-1 with a 5.33 ERA and 33 strikeouts in his career against the Chicago Cubs.

The Chicago Cubs @ Milwaukee Brewers Betting Trends: October 6, 2025

 

Why the Milwaukee Brewers will win

 

Why the Chicago Cubs will win

Total Runs Facts

Milwaukee Brewers Player Prop Facts

Chicago Cubs Player Prop Facts

Matchup/League Facts

Brewers vs Cubs Prediction

The Cubs will have their chances with Imanaga on the mound, as he’s been solid in two years, and he has a 3.44 ERA and .220 allowed batting average in 73.1 road innings. However, the Cubs have lost 4 of Imanaga’s last 5 starts, and he wasn’t great in 4 innings against the Padres, his postseason debut.

I have no idea what to expect from a bullpen game from the Brewers, but they finished the season with the best record in baseball, and they’ve made MLB bettors a pretty penny. Until that stops, you kind of have to keep showing up at the well. It seems like people are writing off the Brewers and aren’t believers in what they accomplished all year. The profit speaks for itself, folks. Give me the Brewers once again.

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