Cardinals vs Athletics Prediction 9/2/25 MLB Picks Today

The Athletics and St. Louis Cardinals meet Tuesday in MLB action at Busch Stadium. Here’s a Cardinals vs Athletics Prediction. This article will include a Cardinals vs Athletics Pick.

Athletics Betting Preview

The Athletics are 64-75 on the year and play the Angels, Red Sox, and Reds next. The Athletics are batting .254 on the season, have a .319 OBP, and a .434 slugging percentage. The Athletics pitching staff has a 4.82 ERA and a 1.37 WHIP. Brent Rooker leads the Athletics with 146 hits and 80 RBI, while Tyler Soderstrom and Jacob Wilson have combined for 264 hits and 136 RBI.

Luis Severino gets the ball for the Athletics, and he is 6-11 with a 4.82 ERA and 103 strikeouts this season. This will be Severino’s second career game against the St. Louis Cardinals.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 68-71 on the year and play the Giants, Mariners, and Brewers next. The St. Louis Cardinals are batting .247 on the season, have a .316 OBP, and a .383 slugging percentage. The St. Louis Cardinals pitching staff has a 4.30 ERA and a 1.31 WHIP. Alec Burleson leads the St. Louis Cardinals with 123 hits and 60 RBI while Masyn Winn and Brendan Donovan have combined for 239 hits and 96 RBI.

Miles Mikolas gets the ball for the St. Louis Cardinals, and he is 6-10 with a 5.04 ERA and 86 strikeouts this season. Mikolas is 0-1 with a 9.00 ERA and 5 strikeouts in his career against the Athletics.

Why the St. Louis Cardinals will win

Why the Athletics will win

St. Louis Cardinals Player Prop Facts

Athletics Player Prop Facts

Cardinals vs Athletics Prediction

The A’s have won four straight games with Severino on the mound, and while his season numbers are shaky, he has a 3.17 ERA and .214 allowed batting average in 65.1 road innings. Severino has been a solid pitcher this season when you take him out of Sacramento. Mikolas isn’t having a great season, and he’s coming off an August where he allowed 29 hits and 15 earned runs in 22.1 innings. In a battle between two bad teams with nothing to play for at this stage, I want the better pitcher. Give me the Athletics.

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