Cardinals vs Brewers Prediction 5/26/26 MLB Picks Today

In this article, we will formulate a Cardinals vs Brewers Prediction for this MLB matchup on Tuesday, May 26^th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Milwaukee Brewers Preview

The Milwaukee Brewers have a 31-20 record this season and are sitting in the first place of the NL Central. They have a 17-11 home record and are coming off a 5-1 home win against the Cardinals. They will face the Astros and the Giants next.

The Brewers have a .248 batting average this season, .334 OBP and .364 Slugging percentage. Milwaukee’s pitching staff has a 3.27 ERA and 1.20 WHIP. William Contreras is the team’s best hitter with a .304 batting average, also leading the team in RBI with 31. Jake Bauers adds a team-high 7 home runs.

Kyle Harrison (L) is the projected starting pitcher for the Brewers, and he has a 5-1 record, 1.77 ERA and 1.07 WHIP.

St. Louis Cardinals Preview

The St. Louis Cardinals have a 29-23 record this season and are sitting in the second place of the NL Central. They have a 16-10 away record and are coming off a 1-5 road defeat against the Brewers. They will face the Cubs and the Rangers next.

The Cardinals have a .239 batting average this season, .320 OBP and .387 Slugging percentage. St. Louis’ pitching staff has a 4.23 ERA and 1.38 WHIP. Jordan Walker is the team’s best hitter with a .297 batting average, also leading the team in RBI with 42 and adding a team-high 15 home runs.

Michael McGreevy (R) is the projected starting pitcher for the Cardinals, and he has a 3-3 record, 2.40 ERA and 0.99 WHIP.

St. Louis Cardinals @ Milwaukee Brewers Betting Trends: May 26, 2026

• Probable Starting Pitcher: Kyle Harrison      Record this season: 5-1      ERA: 1.77
• Home Record: 2-1
• Last 5 against Cardinals: –

Why the Milwaukee Brewers will win

• The Brewers have won each of their last five games against NL Central opponents.
• The Cardinals have lost seven of their last eight night games at American Family Field following a loss.
• The favorites have covered the run line in each of the Brewers’ last five games at American Family Field.
• The Cardinals have failed to cover the run line in four of their last five games.
• The Brewers have won the first inning in each of their last four games as favorites against National League opponents.
• The Brewers have led after 5 innings in each of their last seven games as home favorites.
• The Brewers have led after 3 innings in each of their last eight games against opponents that held a winning record.

• Probable Starting Pitcher: Michael McGreevy      Record this season: 3-3      ERA: 2.40
• Road Record: 2-2
• Last 5 against Brewers: –

Why the St. Louis Cardinals will win

• The Cardinals have won each of their last eight Tuesday games as underdogs.
• The Brewers have lost four of their last five games as favorites against the Cardinals following a win.
• The Brewers have failed to cover the run line in each of their last eight games against the Cardinals following a win.
• The Cardinals have covered the run line in each of their last eight night games following a loss.
• The Cardinals have led after 5 innings in each of their last four night games against the Brewers.
• The Cardinals have led after 3 innings in each of their last five night games against NL Central opponents that held a winning record.

Total Runs Facts

• Each of the Cardinals’ last six road games after playing the previous day have gone UNDER the total runs line.
• Five of the Brewers’ last six games have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Cardinals’ last six night games against NL Central opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Brewers’ last four games as favorites.

Milwaukee Brewers Player Prop Facts

• Christian Yelich has hit a home run in three of the Brewers’ last five home games against the Cardinals.
• Andrew Vaughn has recorded at least one hit in each of his last eight appearances with the Brewers as home favorites against NL opponents.
• Brice Turang ranks 3rd amongst qualified players for On Base Percentage (.410) this season.

St. Louis Cardinals Player Prop Facts

• Alec Burleson has recorded at least one hit in each of the Cardinals’ last eight night games.
• Nolan Gorman has hit a home run in four of the Cardinals’ last five Tuesday games against NL opponents that held a winning record.
• Jordan Walker ranks 4th amongst qualified players for Slugging Percentage (.585) this season.

Matchup/League Facts

• The Brewers rank 30th in the league for home runs this season (35).
• The Brewers rank 1st in the league for home runs allowed this season (37).
• The Cardinals rank 29th in the league for strikeouts this season (392).
• The Cardinals rank T28th in the league for triples this season (3).

Cardinals vs Brewers Prediction

Both teams are tied 4-4 in their last 8 meetings but the Brewers are 4-1 in their last 5 meetings in Milwaukee.

In this Cardinals vs Brewers Prediction, the Brewers are coming as -180 home favorites. The Brewers dominated the opening game of the series and have the pitching edge today with the red-hot Kyle Harrison on the bump, who is coming off back-to-back shutouts. On top of that, the Brewers have a better bullpen and a better offense, with the Cardinals being weaker against lefties. Take the Brewers to win this one at home.