Cardinals vs Diamondbacks Prediction 5/23/25 MLB Picks Today

The Arizona Diamondbacks and St. Louis Cardinals meet Friday in MLB action at Busch Stadium. Here’s a Cardinals vs Diamondbacks Prediction. This article will include a Cardinals vs Diamondbacks Pick.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 26-24 on the year and play the Pirates, Nationals, and Braves next. The Arizona Diamondbacks are batting .254 on the season, have a .290 OBP, and a .416 slugging percentage. The Arizona Diamondbacks pitching staff has a 4.64 ERA and a 1.33 WHIP. Corbin Carroll leads the Arizona Diamondbacks with 58 hits and 34 RBI, while Josh Naylor and Geraldo Perdomo have combined for 106 hits and 66 RBI.


Zac Gallen gets the ball for the Arizona Diamondbacks, and he is 3-5 with a 5.14 ERA and 59 strikeouts this season. Gallen is 1-1 with a 3.12 ERA and 21 strikeouts in his career against the St. Louis Cardinals.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 27-23 on the year and play the Orioles, Rangers, and Royals next. The St. Louis Cardinals are batting .263 on the season, have a .334 OBP, and a .404 slugging percentage. The St. Louis Cardinals’ pitching staff has a 3.73 ERA and a 1.21 WHIP. Brendan Donovan leads the St. Louis Cardinals with 61 hits and 22 RBI, while Lars Nootbaar and Willson Contreras have combined for 94 hits and 53 RBI.

Miles Mikolas gets the ball for the St. Louis Cardinals, and he is 3-2 with a 3.77 ERA and 27 strikeouts this season. Mikolas is 2-2 with a 3.26 ERA and 22 strikeouts in his career against the Arizona Diamondbacks.

Why the St. Louis Cardinals will win

Why the Arizona Diamondbacks will win

St. Louis Cardinals Player Prop Facts

Arizona Diamondbacks Player Prop Facts

Cardinals vs Diamondbacks Prediction

The Diamondbacks are getting the benefit of the doubt with Gallen on the mound, but he’s just been a name this season. Gallen has a 5.14 ERA and 1.38 WHIP this season, and he just allowed six runs against the Rockies through five innings. Gallen has walked 25 batters in 56 innings and has allowed 10 homers. He hasn’t been great. Mikolas is an all-star caliber pitcher when he’s right, and he’s allowed 10 hits and four runs in his last 16.1 innings. Mikolas just shut out the Royals through six innings. The Cardinals at home with the plus money is one of the better value bets on Friday’s MLB card.

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