Cardinals vs Marlins Prediction 8/20/25 MLB Picks Today

In this article, we will formulate a Cardinals vs Marlins Prediction for this MLB game on Wednesday, August 20th at the loanDepot park in the third game of this series, with the Cardinals having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.

Miami Marlins Preview

The Miami Marlins have a 59-67 record this season and are sitting on the third place of the NL East. The Marlins have a 28-33 home record and are 61-62 in over/under. They are coming off a 4-7 home defeat by the Cardinals, and are 2-8 in their last 10 games. Over is 3-1 in their last 4 games and are playing the Blue Jays and the Braves next.


The Marlins have a .251 batting average this season, .314 OBP and .396 slugging percentage. Miami’s pitching staff has a 4.54 ERA and 1.30 WHIP.  Xavier Edwards leads the Marlins with 136 hits and is the team’s best hitter with a .304 batting average. Kyle Stowers adds team-highs in RBI with 73 and in home runs with 25.

Sandy Alcantara (R) is the projected starting pitcher for the Marlins, and he has a 6-11 record, 6.31 ERA and 1.41 WHIP.

St. Louis Cardinals Preview

The St. Louis Cardinals have a 63-64 record this season and are sitting on the 4th place of the NL Central. The Cardinals have a 28-34 road record and are 64-57 in over/under They are coming off a 7-4 road victory over the Marlins, and have back-to-back wins. Over is 5-1 in their last 6 games and are playing the Pirates and the Rays next.

The Cardinals have a .250 batting average this season, .319 OBP and .387 Slugging percentage. St. Louis’ pitching staff has a 4.23 ERA and 1.29 WHIP. Brendan Donovan leads the Cardinals with 118 hits, while Alec Burleson is the team’s best hitter with a .287 batting average. Wilson Contreras leads the team in RBI, with 66, adding a team-high 16 home runs.

Andre Pallante (R) is the projected starting pitcher for the Cardinals, and he has a 6-10 record, 5.04 ERA and 1.38 WHIP.

Why the Miami Marlins will win

Why the St. Louis Cardinals will win

Total Runs Facts

Matchup/League Facts

Cardinals vs Marlins Prediction

The Marlins are 4-3 in their last 7 meetings against the Cardinals, but the Cardinals are 3-2 in their last 5 meetings in Miami. Over is 4-1 in their last 5 meetings in Miami.

In this Cardinals vs Marlins Prediction, the Marlins are coming as -130 home favorites. In no way shape or form I am going to back Sandy Alcantara, especially as a favorite. He might be better at home, with a 5.09 home ERA, but Pallante has also been better on the road, with a 4.73 ERA. I don’t trust either pitcher in this matchup, as they are both volatile and can give up 5+ runs, and Pallante is coming into this matchup in terrible form, with 10 earned runs in his last two starts. Both teams are better against righties, averaging 9.4 runs per game combined against right-handed pitching. The total for some reason is set only at 8 runs, and both games of this series had 11 total runs each. Take the over 8 in this one.

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