Cardinals vs Reds Prediction 6/5/26 MLB Picks Today

In this article we will formulate a Cardinals vs Reds prediction for this MLB game on Friday, June 5th at Busch Stadium in St. Louis, Missouri. Let’s take a look at the prediction for this MLB matchup. 

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 32-28 this season after they lost two out of three against the Rangers by scores of 1-2, 4-7, and 5-3. In game three, St. Louis was tied at one in the third inning, but they scored the next four runs to pull away with the win. The Cardinals recorded 11 hits and they committed one error in the game, while they were led by Burleson, who went 2-4 with three RBIs. Pallante allowed three hits and one earned run over 5.2 innings for the win, while O’Brien picked up the save. Prior to that series, St. Louis won two out of three against the Cubs, but lost all three against the Brewers before that. 

This season, St. Louis has a 4.14 ERA with a 1.36 WHIP and a .254 opponent batting average, while they have scored 257 runs with a .240 batting average and a .317 on base percentage. Jordan Walker has led the Cardinals with 15 home runs and 44 RBIs, while Alec Burleson has added seven home runs and 42 RBIs. The projected starting pitcher for St. Louis is Kyle Leahy, who is 5-3 with a 4.25 ERA and a 1.56 WHIP over 55.0 innings pitched this season. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 31-30 this year after they lost two out of three against the Royals by scores of 2-9, 4-3, and 2-5. In game three, Cincinnati tied the game at two in the fifth inning, but they allowed three runs in the ninth for the loss. The Reds recorded eight hits and they committed one error in the game, while they were led by Dunn, who went 2-5 with one home run and two RBIs. Burns allowed four hits and two earned runs over 6.0 innings, while Santillan allowed three earned runs for the loss. Prior to that series, Cincinnati lost two out of three against the Braves, but did win two out of three against the Mets before that. 

This season, Cincinnati has a 4.76 ERA with a 1.45 WHIP and a .249 opponent batting average, while they have scored 264 runs with a .229 batting average and a .312 on base percentage. Elly De La Cruz has led the Reds with 12 home runs and 37 RBIs, while Sal Stewart has added 12 home runs and 37 RBIs. The projected starting pitcher for Cincinnati is Brady Singer, who is 2-5 with a 6.18 ERA and a 1.69 WHIP over 51.0 innings pitched this year. 

Why the St. Louis Cardinals will win

Why the Cincinnati Reds will win

Total Runs Facts

St. Louis Cardinals Player Prop Facts

Cincinnati Reds Player Prop Facts

Matchup/League Facts

Cardinals vs Reds Prediction 

St. Louis comes into this matchup after losing a series to the Rangers, but they have scored 4+ runs in three of their last four games. The Cardinals are 16-16 at home this year, while the Reds are 15-14 on the road. Cincinnati has alternated wins and losses over their last five games, but they have allowed 5+ runs in three of those five. The Reds are starting Singer, who has allowed 3+ earned runs in five straight starts, while Leahy has allowed one earned run or fewer in four of his last five outings. Take the Cardinals at home here. 

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