Cardinals vs Royals Prediction 6/4/25 MLB Picks Today

The Kansas City Royals and the St. Louis Cardinals meet Wednesday in MLB action from Busch Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cardinals vs Royals Prediction.

Starting Pitching Matchup

The Kansas City Royals will send out Noah Cameron for the start here, and Cameron is 2-1 with a 1.05 ERA and 16 strikeouts this season. This will be Cameron’s second career start against the Cardinals. Miles Mikolas will get the start for the Cards here and is 4-2 with a 3.90 ERA and 34 strikeouts this season. In his career, Mikolas is 3-0 with a 1.67 ERA and 26 strikeouts against the Royals.

Kansas City Royals Recap

The Kansas City Royals come into this game looking to build on their 10-7 win over the Cardinals to start the series on Tuesday to improve to 32-29 on the year. After this series, the Royals will head on the road for a set against the Chicago White Sox.

Royals Alternate Wins & Losses In 6 Straight

Bobby Witt Jr. has a team-high 66 hits with 22 doubles and 20 stolen bases, along with 3 triples, 6 home runs, and 31 RBIs, while Vinnie Pasquantino has 58 hits with 6 doubles, a triple, 8 home runs, and 31 RBIs. Maikel Garcia added 66 hits with 14 doubles, 5 home runs, and 25 RBIs and 10 stolen bases, and Salvador Perez also has 4 home runs and 26 RBIs but also has the unfortunate distinction of leading the Royals with 50 strikeouts so far this season.

Why the Kansas City Royals will win

Kansas City Royals Player Prop Facts

St. Louis Cardinals Recap

The St. Louis Cardinals come into this game looking to bounce back from a 10-7 loss at the hands of Kansas City last time out to slip to 33-27 on the year. After this series, the Cardinals will square off against the Los Angeles Dodgers at home.

Cardinals Trying To Find Some Consistency

Brendan Donovan has a team-high 70 hits along with 19 doubles, 4 home runs, and 24 RBIs, while Lars Nootbaar has 56 hits with 8 home runs, 28 RBIs, 12 doubles, and 4 stolen bases. Nolan Arenado also has 47 hits with 10 doubles, 6 home runs, and 27 RBIs of his own, and Victor Scott II has 45 hits with 8 doubles, a triple, 19 RBIs, and a team-high 16 stolen bases. Willson Contreras has also chipped in 50 hits with 6 home runs and 31 RBIs of his own this season.

Why the St. Louis Cardinals will win

St. Louis Cardinals Player Prop Facts

Total Runs Facts

Cardinals vs Royals Prediction

I’m backing the Royals in this one. Cameron’s been solid out of the gate, and the Royals’ bullpen has been able to hold it down as of late as well. Mikolas is pitching a little above his pay grade as far as I’m concerned, and I think that the Royals could break through and get to him here. I’ll roll with the Royals in this one to get the job done.

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