White Sox vs Cubs Prediction 7-27-25 MLB Picks

The Chicago Cubs and the Chicago White Sox meet Sunday in MLB action from Rate Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a White Sox vs Cubs Prediction.

Starting Pitching Matchup

The Chicago Cubs did not have a starting pitcher announced at the time that this article was posted. Sean Burke will get the start for the White Sox here and is 4-8 with a 4.19 ERA and 85 strikeouts this season. This will be Burke’s second career start against the Cubs.

Chicago Cubs Recap

The Chicago Cubs come into this game looking to build on their 6-1 win over the White Sox to sit at 61-43 on the year. After this series, the Cubs will head on the road for a series against the Milwaukee Brewers.

Cubs Looking To Avoid Back-To-Back Series Losses

Ian Happ has 83 hits with 16 doubles, 13 home runs, and 48 RBIs. Kyle Tucker has 103 hits, including 19 doubles, 4 triples, 18 home runs, and 58 RBIs, while Seiya Suzuki also has 100 hits with 24 doubles and 26 home runs and 81 RBIs of his own. Pete Crow-Armstrong also has contributed 106 hits, 25 doubles, 4 triples, 27 home runs, and 74 RBIs this season. Dansby Swanson has added 16 home runs and 47 RBIs, while also having 115 strikeouts, and Suzuki has a team-high 114 strikeouts so far this season. Crow-Armstrong also has a team-high 28 stolen bases, while Nico Hoerner has 19 stolen bases this season. Tucker’s also added 23 stolen bases while Michael Busch has also chipped in 15 doubles, 3 triples, 20 home runs, and 60 RBIs this season.

Why the Chicago Cubs will win

• The White Sox have lost 18 of their last 19 home games against NL Central opponents following a loss.
• The Cubs have won each of their last seven games against the White Sox following a win.
• The road team has covered the run line in seven of the White Sox’s last eight games.
• The White Sox have failed to cover the run line in four of their last five day games against NL Central opponents that held a winning record.

Chicago Cubs Player Prop Facts

• Carson Kelly has recorded a Double in three of his last four appearances in day games against AL Central teams that held a losing record.
• Ian Happ has hit a home run in three of the Cubs’ last five road games against the White Sox.
• Kyle Tucker has recorded at least one hit in each of his last 11 appearances at Rate Field.

Chicago White Sox Recap

The Chicago White Sox come into this game looking to rebound from their loss at the hands of the Cubs on Saturday to sit at 38-67 on the year. After this series, the White Sox will square off against the Philadelphia Phillies at home.

White Sox Looking For Third Straight Series Win

Lenyn Sosa has 83 hits, including 16 doubles and 37 RBIs. Andrew Benintendi has 62 hits, including 12 doubles, 11 home runs, 38 RBIs, and a .235 batting average, while Miguel Vargas has 84 hits, 25 doubles, 12 home runs, and 41 RBIs. Brooks Baldwin has also added 24 RBIs, while Luis Robert Jr. has a team-high 26 stolen bases along with 41 RBIs so far this season. Chase Meidroth has added 75 hits with 11 stolen bases as well as 11 doubles this season.

Why the Chicago White Sox will win

• The Cubs have lost seven of their last eight day games against AL Central opponents following a road win.
• The White Sox have won each of their last five day games against teams that held a winning record.
• The Cubs have failed to cover the run line in each of their last six games against AL Central opponents following a win.
• The White Sox have covered the run line in 10 of their last 11 day games following a home loss.

Chicago White Sox Player Prop Facts

• Michael A. Taylor has recorded a Double in four of his last five appearances against NL opponents.
• Mike Tauchman has hit a home run in each of the White Sox’s last three games against NL Central opponents.
• Andrew Benintendi has recorded at least one hit in each of his last 11 appearances against NL Central opponents that held a winning record.

Total Runs Facts

• Nine of the Cubs’ last 10 road games against AL Central opponents have gone UNDER the total runs line.
• Each of the White Sox’s last four day games against National League opponents have gone UNDER the total runs line.

White Sox vs Cubs Prediction

I’m on the over in this one. I get the case to be made for either side here, but the price feels a bit steep for me, with the Cubs without confirmation of a starting pitcher. The White Sox just aren’t a team I feel like getting behind consistently. That being said, these are two teams that are still swinging a hot bat in fairness, and I think that these two sides can keep the ball rolling here to get us some runs in this one. Give me the over here.