Chicago White Sox vs. Los Angeles Angels Prediction 5-29-23 MLB Picks

Chicago White Sox vs. Los Angeles Angels Prediction 5-29-23 MLB Picks player photo
Credit: USA Today Sports

The Los Angeles Angels and the Chicago White Sox meet in MLB action from Guaranteed Rate Field on Monday night. Let’s dive into the odds, starting pitching matchup, history and make a prediction for this game.


The White Sox are listed as -135 home favorites while the Angels have +115 road underdogs. The total for this game is set at 8.5 runs.

Starting Pitching Matchup

Los Angeles will send Griffin Canning to the mound here and is 3-2 with a 4.95 ERA and 30 strikeouts this season. Michael Kopech will start here for the White Sox and is 3-4 with a 4.24 ERA and 60 strikeouts this season.

Matchup History

The Angels’ 4-1 win back on June 29th, 2022, made it 7 straight meetings without back-to-back winners in this head-to-head matchup.


Los Angeles is 7-1 in their last 8 series-opening games and 1-4 in their last 5 games against a team with a losing record while the over is 9-1-1 in their last 11 Monday games. Chicago is 5-1 in their last 6 home games and 5-0 in their last 5 home games against a team with a right-handed starter while the under is 7-3 in their last 10 games overall.


I’m backing the White Sox here. Chicago burned me by falling short against the Tigers, but I feel they have a massive pitching edge here and I never thought I’d say that with Michael Kopech, but Kopech’s turned it around in recent starts. Griffin Canning hasn’t been great so far this season and I just don’t see it happening here against a White Sox team that’s started to find themselves in recent weeks.

Chris Ruffolo's Free Pick:Chicago White Sox -135