Cincinnati Reds vs. St. Louis Cardinals Prediction 05-23-2023 MLB Picks

Chris RuffoloMay 23, 2023
Cincinnati Reds vs. St. Louis Cardinals Prediction 05-23-2023 MLB Picks player photo
Credit: USA Today Sports

The St. Louis Cardinals and the Cincinnati Reds meet in an NL Central division matchup in MLB action from Great American Ballpark on Tuesday. Let’s dive into the odds, starting pitching matchup, history and make a prediction for this game.


St. Louis is listed as a -150 road favorite while Cincinnati is a +130 home underdog. The total for this game is set at 10 runs.

Starting Pitching Matchup

Adam Wainwright will start for the Cardinals here and is 1-0 with a 5.74 ERA and 8 strikeouts this season. Graham Ashcraft will get the start for the Reds and is 2-2 with a 4.84 ERA and 36 strikeouts this season.

Matchup History

Cincinnati’s 6-5 win on Monday made it back-to-back wins for the Reds in this head-to-head matchup over the Cardinals.


St. Louis is 5-2 in their last 7 road games and 11-4 in their last 15 games overall while the over is 7-1 in their last 8 games following a loss. Cincinnati is 9-25 in their last 34 division games and 2-6 in their last 8 games following a win while the over is 13-5 in their last 18 games following a win.


I’m rolling with the over here. I don’t trust the pitching matchup at all, as Adam Wainwright hasn’t looked good since debuting this season, and Graham Ashcraft had this happen to him last year, where he started well and didn’t really look right after he got roughed up for the first time. I think this is going to be a fairly high-scoring game and I think we can get into the 11 or 12 run range here. Give me the over here.

Chris Ruffolo's Free Pick:Over 10
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Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg