The San Diego Padres and the Colorado Rockies meet Wednesday in MLB action from Coors Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Diego Padres vs. Colorado Rockies prediction.
Starting Pitching Matchup
The San Diego Padres will start Walker Buehler for the start here and Buehler is 1-1 with a 4.58 ERA and 18 strikeouts this season. Tomoyuki Sugano will start for the Rockies here and is 1-1 with a 3.92 ERA and 15 strikeouts this season.
San Diego Padres Recap
The San Diego Padres come into this game looking to add on to their 1-0 win over Colorado last time out to sit at 16-7 this season. After this series, the Padres will head on the road for a series against the Arizona Diamondbacks.
Padres Continue To Roll
Entering Tuesday, Jackson Merrill has 19 hits with 6 doubles, 3 home runs and 13 RBIs while Ramon Laureano has 21 hits with 4 doubles, a triple, 4 home runs and 15 RBIs as well on the year. Fernando Tatis Jr. has 20 hits with 4 doubles and 12 RBIs and Xander Bogaerts has 21 hits with 2 doubles, 3 home runs and 14 RBIs. Manny Machado also has 13 hits with 2 doubles, 2 home runs and 10 RBIs as well on the year.
Colorado Rockies Recap
The Colorado Rockies come into this game looking to shake off their loss at the hands of the Padres in Tuesday’s opener to fall to 9-15 this season. After this series, the Rockies will head on the road for a series against the New York Mets.
Rockies Drop 7 Of Last 10
Going into Tuesday, TJ Rumfield has 20 hits with a double, a triple, 3 home runs and 11 RBIs while Ezequiel Tovar has 19 hits with 8 doubles, a home run and 6 RBIs. Hunter Goodman’s added 19 hits with 4 doubles, 5 home runs and 8 RBIs and Jordan Beck has 7 RBIs as well on the year. Troy Johnston has 21 hits with 6 doubles, 2 home runs and 10 RBIs. Willi Castro also has 15 hits with 4 doubles, a home run and 8 RBIs.
San Diego Padres @ Colorado Rockies Betting Trends: April 22, 2026
- Probable Starting Pitcher: Tomoyuki Sugano Record this season: 1-1 ERA: 3.92
- Home Record: 1-1
- Last 5 against Padres: 0-0
Why the Colorado Rockies will win
- The Rockies have won six of their last nine games as home underdogs.
- The Padres have lost six of their last eight night games at Coors Field following a road win.
- The home team has covered the run line in each of the last seven games between the Padres and Rockies.
- The Padres have failed to cover the run line in seven of their last eight night games at Coors Field following a road win.
- Probable Starting Pitcher: Walker Buehler Record this season: 1-1 ERA: 4.58
- Road Record: 0-0
- Last 5 against Rockies: 1-2
Why the San Diego Padres will win
- The Padres have won each of their last nine games against teams that held a losing record.
- The Rockies have lost 20 of their last 21 Wednesday night games against teams that held a winning record.
- The Padres have covered the run line in seven of their last eight games against National League opponents after playing the previous day.
- The Rockies have failed to cover the run line in each of their last six Wednesday night games.
- The Rockies have trailed after 3 innings in eight of their last nine games.
- The Rockies have trailed after 5 innings in seven of their last eight night games against National League opponents that held a winning record.
Total Runs Facts
- Each of the Padres’ last five games have gone UNDER the total runs line.
- Five of the Rockies’ last six night games as underdogs have gone UNDER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Padres’ last 11 road games.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Rockies’ last eight Wednesday games against National League opponents.
Colorado Rockies Player Prop Facts
- Hunter Goodman has hit a home run in three of his last four home appearances against the Padres.
- Tyler Freeman has recorded at least one hit in each of his last 12 Wednesday appearances against teams that held a winning record.
San Diego Padres Player Prop Facts
- Manny Machado has hit a home run in three of his last five appearances against the Rockies after playing the previous day.
- Fernando Tatis Jr. has recorded two or more hits in each of the Padres’ last three games against the Rockies.
- Fernando Tatis Jr. ranks T10th in the league in Steals (6) this season.
Matchup/League Facts
- The Rockies rank 29th in the league for strikeouts against this season (229).
- The Rockies rank 28th in the league for walks this season (66).
- The Padres rank T1st in the league for home runs allowed this season (13).
- The Padres rank T1st in the league for runs allowed this season (79).
San Diego Padres vs. Colorado Rockies Prediction
I’m on the Padres here. I just think they’re playing the better baseball right now and while Walker Buehler is not the dominant ace level starter he once was, I still think he’s a quality option in this game that can give the Padres some solid innings before handing it off to the clearly better bullpen in this game. Give me the Padres here.