Cubs vs Cardinals Prediction 5/31/26 MLB Picks Today

In this article, we will formulate a Cubs vs Cardinals Prediction for this MLB matchup on Sunday, May 31st in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

St. Louis Cardinals Preview

The St. Louis Cardinals have a 30-26 record this season and are sitting in the 3rd place of the NL Central. They have a 14-14 home record and are coming off a 1-6 home defeat against the Cubs. They will face the Rangers and the Reds next.

The Cardinals have a .238 batting average this season, .317 OBP and .384 Slugging percentage. St. Louis’ pitching staff has a 4.21 ERA and 1.37 WHIP. Jordan Walker is the team’s best hitter with a .290 batting average, also leading the team in RBI with 42 and adding a team-high 15 home runs.

Matthew Liberatore (L) is the projected starting pitcher for the Cardinals, and he has a 2-3 record, 4.76 ERA and 1.57 WHIP.

Chicago Cubs Preview

The Chicago Cubs have a 32-27 record this season and are sitting in the 2nd place of the NL Central. They have a 14-16 road record and are coming off a 6-1 road win against the Cardinals. They will face the Athletics and the Giants next.

The Cubs have a .240 batting average this season, .337 OBP and .389 Slugging percentage. Chicago’s pitching staff has a 4.17 ERA and 1.23 WHIP. Alex Bregman is the team’s best hitter with a .260 batting average. Michael Busch leads the team in RBI with 35, while Ian Happ adds a team-high 13 home runs.

Jordan Wicks (L) is the projected starting pitcher for the Cubs, and he has a 0-1 record, 16.62 ERA and 2.31 WHIP.

The Chicago Cubs @ St. Louis Cardinals Betting Trends: May 31, 2026

 

Why the St. Louis Cardinals will win

 

Why the Chicago Cubs will win

Total Runs Facts

St. Louis Cardinals Player Prop Facts

Chicago Cubs Player Prop Facts

Matchup/League Facts

Cubs vs Cardinals Prediction

The Cubs are 4-1 in their last 5 meetings against the Cardinals but both teams are tied 2-2 in their last 4 meetings in Saint Louis.

In this Cubs vs Cardinals Prediction, the Cubs are coming as -115 road favorites. I don’t trust either pitcher in this matchup, as Wicks was shelled in his first start of the season with 8 earned runs, while Liberatore has 11 earned runs across his last three starts and has been weaker at home. Chicago’s offense has come back to life lately, as they have scored 28 total runs in their last four games and I expect them to get to Liberatore. Take the over 9 in this one.

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