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Cubs vs Red Sox Prediction 7/20/25 MLB Picks Today

Boston Red Sox (53-47) vs. Chicago Cubs (59-39)
July 20, 2025 2:20 pm EDT
The Line: Chicago Cubs +115 / Boston Red Sox -135; Over/Under: 7
(Get latest betting odds)

In this article we will formulate a Cubs vs Red Sox prediction for this MLB game on Sunday, July 20th at Wrigley Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Chicago Cubs Betting Preview

The Chicago Cubs are 59-39 this year after they won the first two games of the series by scores of 4-1 and 6-0. In their game two win, Chicago jumped out to a 2-0 lead in the first inning and never looked back in the win. The Cubs recorded 11 hits and they committed one error in the game, while they were led by Busch, Tucker, Crow-Armstrong, Shaw, and Happ, who all hit a home run in the win. Chicago started Imanaga, who allowed five hits and zero earned runs over 7.0 innings for the win, while Keller and Brasier closed out the game. 

Prior to this series, the Cubs won two out of three against the Yankees, but did lose two out of three against the Twins before that. Chicago has won four games in a row and they are currently first in the NL Central standings. The Chicago pitching staff has a 3.77 ERA with a 1.22 WHIP and a .245 opponent batting average, while their offense has scored 522 runs with a .256 batting average and a .325 on base percentage this season. Seiya Suzuki has led Chicago with 26 home runs and 80 RBIs, while Pete Crow-Armstrong has added 26 home runs and 72 RBIs this year. The projected starting pitcher for Chicago is Cade Horton, who is 3-3 with a 4.45 ERA and a 1.41 WHIP over 56.2 innings pitched this year. 

Boston Red Sox Betting Preview

The Boston Red Sox are 53-47 this season after they lost game two by a score of 6-0 on Saturday. Boston fell behind early in the game and they never found any offense in the blowout loss. The Red Sox recorded six hits in the game and they were led by Yoshida and Toro, who both had two hits in the loss. Boston started Bello, who allowed six hits and three earned runs over 6.0 innings for the loss, while Murphy allowed three earned runs in relief. 

Prior to this series, the Red Sox swept the Rays in four games and also swept the Rockies in three games. Boston has won 10 of their last 12 games and they are currently third in the AL East standings. The Boston pitching staff has a 3.82 ERA with a 1.30 WHIP and a .246 opponent batting average, while their offense has scored 492 runs with a .255 batting average and a .325 on base percentage this season. Wilyer Abreu has led Boston with 18 home runs and 52 RBIs, while Trevor Story has added 15 home runs and 58 RBIs this year. The projected starting pitcher for Boston is Garrett Crochet, who is 10-4 with a 2.23 ERA and a 1.04 WHIP over 129.1 innings pitched this season. 

Why the Red Sox will beat the Cubs

  • The Red Sox have won each of their last 11 Sunday day games against NL Central opponents.
  • The Cubs have lost four of their last five day games against AL East opponents following a home win.
  • The Cubs have failed to cover the run line in each of their last six day games against AL East opponents following a home win.
  • The Red Sox have covered the run line in each of their last six Sunday road games against NL Central opponents.
  • The Red Sox have led after 3 innings in four of their last five day games against National League opponents.
  • The Red Sox have led after 5 innings in three of their last four day games against National League opponents.

Total Runs Facts

  • Each of the Cubs’ last eight day games against AL East opponents have gone UNDER the total runs line.
  • Each of the Red Sox’s last four games have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Cubs’ last nine day games at Wrigley Field.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the Red Sox’s last 11 road games against National League opponents.

Chicago Cubs Player Prop Facts

  • Kyle Tucker has hit a home run in three of the Cubs’ last four home games against AL opponents that held a winning record.
  • Seiya Suzuki has recorded a Double in three of the Cubs’ last four day games against opponents that held a winning record.
  • Nico Hoerner has recorded at least one hit in each of his last 14 Sunday appearances at Wrigley Field.

Boston Red Sox Player Prop Facts

  • Ceddanne Rafaela has recorded at least one hit in each of his last 12 appearances.
  • Triston Casas has hit a home run in four of his last five road appearances against NL Central opponents.

Cubs vs Red Sox Prediction 

Chicago comes into this contest looking for their fifth win in a row, as they try to complete the series sweep. The Cubs are 32-16 at home this year, while the Red Sox are 21-27 on the road. Boston was red hot coming into this series, but they are in danger of falling into fourth place in the East. The Red Sox are starting Crochet, who has allowed two earned runs or fewer in four of his last five starts. The Cubs are starting Horton, who has allowed 4, 0, and 7 earned runs in his last three outings. Take the Red Sox here. 

David Racey's Free Pick: Red Sox ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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