Detroit Tigers vs. Chicago White Sox Prediction 5-28-23 MLB Picks

Detroit Tigers vs. Chicago White Sox Prediction 5-28-23 MLB Picks player photo
Credit: USA Today Sports

The Chicago White Sox and the Detroit Tigers meet in an AL Central division matchup in MLB action from Comerica Park on Sunday. Let’s dive into the odds, starting pitching matchup, history and make a prediction for this game.


The Tigers are -115 home favorites while Chicago is a -105 road underdog. The total for this game is set at 8 runs.

Starting Pitching Matchup

Dylan Cease will start for the White Sox and is 3-3 with a 4.60 ERA and 60 strikeouts this season. Eduardo Rodriguez will get the start for the Tigers and is 4-4 with a 2.19 ERA and 61 strikeouts this season.

Matchup History

Detroit’s 7-3 win on Saturday made it five wins in the last six head-to-head meetings against the White Sox.


Chicago is 5-0 in their last 5 games following a loss and 6-15 in their last 21 road games while the under is 7-3 in their last 10 games overall. Detroit is 1-4 in their last 5 games following a win and 28-60 in their last 88 Sunday games while the over is 4-0 in their last 4 division games.


I’m backing the White Sox here. The Sox already took out a lefty for the Tigers earlier in this series in Joey Wentz, and while Eduardo Rodriguez is having a far better season compared to Wentz, the White Sox are still hitting well right now and as much progress as the Tigers have made, it’s hard to back them here in a matchup against Dylan Cease, who has owned the Tigers over the course of his career. I just don’t see this as a viable spot to back Detroit, so give me Chicago here.

Chris Ruffolo's Free Pick:Chicago -105