Diamondbacks vs Cubs Prediction 3/30/25 MLB Picks Today

The Chicago Cubs and the Arizona Diamondbacks meet Sunday in MLB action from Chase Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Chicago Cubs vs. Arizona Diamondbacks prediction.

Starting Pitching Matchup

Matthew Boyd will get the start for the Cubs here and Boyd was 2-2 with a 2.72 ERA and 46 strikeouts last season. In his career, Boyd is 0-2 with a 6.55 ERA and 9 strikeouts against Arizona. Eduardo Rodriguez will get the start for the Diamondbacks here and Rodriguez was 3-4 with a 5.04 ERA and 47 strikeouts last season. This will be Rodriguez’s second career start against the Cubs.

Chicago Cubs Recap

The Chicago Cubs come into this one looking to win the series after taking the lead with a 4-3 win in Saturday’s matchup. After this series, the Cubs will head on the road for an interleague series against the Athletics.

Cubs Looking For First Series Win Of The Season

Kyle Tucker leads the Cubs with 5 hits including a pair of doubles, a home run and 4 RBIs while Ian Happ has 4 hits with a double, a home run and 4 RBIs as well. Miguel Amaya has a team-high 4 doubles and 7 RBIs while Seiya Suzuki has the dubious distinction has a team-high 11 strikeouts and Jon Berti’s logged a team-leading 2 stolen bases. Berti and Michael Busch each have 4 hits as well this season.

Why the Chicago Cubs will win

• The underdogs have won nine of the Cubs’ last 11 games at Chase Field.
• The Diamondbacks have lost five of their last seven games as home favorites against NL Central opponents.
• The underdogs have covered the run line in 12 of the Cubs’ last 13 games at Chase Field.
• The Diamondbacks have failed to cover the run line in 13 of their last 15 games as home favorites against NL Central opponents.

Chicago Cubs Player Prop Facts

• Kyle Tucker has hit a home run in each of his last two appearances in day games against NL teams that held a losing record.
• Justin Turner has recorded at least one Double in three of his last four appearances at Chase Field against opponents that held a losing record.
• Matthew Boyd has recorded a win in four of his last five road appearances against NL opponents.
• Kyle Tucker has recorded at least one RBI in four of his last five appearances against NL West opponents that held a losing record.
• Justin Turner has recorded at least one Single in each of his last seven road appearances.
• Kyle Tucker has scored at least one run in each of his last nine Sunday appearances.
• Matthew Boyd has recorded five or more strikeouts in seven of his last eight appearances.
• Dansby Swanson has recorded at least one hit in each of his last 10 appearances in day games against NL West teams that held a losing record.
• Kyle Tucker ranks T5th in the league in Hits (5) this season.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to salvage a season-opening series split after their loss to the Cubs in Saturday’s matchup. After this game, the Diamondbacks will head on the road for an interleague series against the New York Yankees.

Diamondbacks Searching For Split

Ketel Marte has a team-high 5 hits with a pair of doubles while Eugenio Suarez has 4 hits with all four hits going for home runs with a team-high 7 RBIs. Josh Naylor has 4 hits with a double and Geraldo Perdomo also has 3 hits with 3 RBIs. Pavin Smith, Randal Grichuk and Alek Thomas all have a pair of doubles as well for the Diamondbacks up to this point in the year.

Why the Arizona Diamondbacks will win

• The Diamondbacks have won each of their last 10 day games against National League opponents following a home loss.
• The Cubs have lost each of their last four road games following a win.
• The Cubs have failed to cover the run line in each of their last five day games against NL West opponents following a win.
• The Diamondbacks have covered the run line in six of their last seven day games against National League opponents that held a losing record.

Arizona Diamondbacks Player Prop Facts

• Eugenio Suarez has hit at least one home run in each of the Diamondbacks’ last four games as favorites.
• Randal Grichuk has recorded a Double in each of his last six home appearances against opponents that held a losing record.
• Eduardo Rodriguez has recorded a win in each of his last five appearances in day games against teams that held a losing record.
• Eugenio Suarez has recorded at least one RBI in each of the Diamondbacks’ last six day games.
• Eugenio Suarez has scored at least one run in each of the Diamondbacks’ last four games.
• Josh Naylor has recorded at least one Single in each of his last eight appearances after playing the previous day.
• Eduardo Rodriguez has recorded five or more strikeouts in each of his last 14 appearances against opponents that held a losing record.
• Josh Naylor has recorded at least one hit in each of his last nine appearances against NL Central opponents that held a losing record.
• Eugenio Suarez ranks 1st in the league in Home Runs (4) this season.

Total Runs Facts

• Each of the Cubs’ last seven day games against National League opponents have gone UNDER the total runs line.
• Each of the Diamondbacks’ last six day games after playing the previous day have gone OVER the total runs line.

Chicago Cubs vs. Arizona Diamondbacks Prediction

I’m on the Diamondbacks in this game. I get the case to be made for the Cubs considering they’ve been the better team the last couple of games in this series, but I’m not a Matthew Boyd fan whatsoever and I just think that the Diamondbacks are the better team in this game. I also trust the Diamondbacks’ bats against Chicago’s bullpen compared to Chicago breaking down Rodriguez and Arizona’s pen here as well. I think that the Diamondbacks salvage the split at home here, so give me Arizona in this one.