Diamondbacks vs Giants Prediction 9/8/25 MLB Picks Today

In this article, we will formulate a Diamondbacks vs Giants Prediction for this MLB game on Monday, September 8th at the Oracle Park in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

San Francisco Giants Preview

The San Francisco Giants have a 72-71 record this season and are sitting on the third place of the NL West. They have a 35-34 home record and are 67-70 in over/under. They are coming off a 3-4 road defeat by the Cardinals, and have back-to-back losses. Over is 6-3 in their last 9 games and are playing the Dodgers and the Diamondbacks next.


The Giants have a .239 batting average this season, .314 OBP and .390 Slugging percentage. San Francisco’s pitching staff has a 3.76 ERA and 1.29 WHIP.  Heliot Ramos leads the Giants with 145 hits and is the team’s best hitter, with a .267 batting average. Willy Adames leads the team in RBI with 78, adding a team-high 27 home runs.

Logan Webb (R) is the projected starting pitcher for the Giants, and he has a 13-9 record, 3.17 ERA and 1.23 WHIP.

Arizona Diamondbacks Preview

The Arizona Diamondbacks have a 72-72 record this season and are sitting on the 4th place of the NL West. The Diamondbacks have a 34-38 road record and are 68-67 in over/under They are coming off a 4-7 home defeat by the Red Sox, that ended their four-game winning streak. Under is 6-4-1 in their last 11 games and are playing the Twins and the Giants next.

The Diamondbacks have a .250 batting average this season, .323 OBP and .435 slugging percentage. Arizona’s pitching staff has a 4.43 ERA and 1.32 WHIP. Geraldo Perdomo leads the Diamondbacks with 150 hits, adding a team-high 91 RBI. He is also the team’s best hitter with a .284 batting average. Corbin Carroll leads the team in home runs with 29.

Reliever Nabil Crismatt (R) is the projected starting pitcher for the Diamondbacks, and he has a 2-0 record, 2.14 ERA and 1.33 WHIP.

Arizona Diamondbacks @ San Francisco Giants Betting Trends: September 8, 2025

 

Why the San Francisco Giants will win

 

Why the Arizona Diamondbacks will win

Total Runs Facts

San Francisco Giants Player Prop Facts

Arizona Diamondbacks Player Prop Facts

Matchup/League Facts

Diamondbacks vs Giants Prediction

Both teams are tied 5-5 wins in their last 10 head-to-head meetings, but the Dbacks are 2-1 in their last 5 meetings in San Francisco. Over is 7-2-1 in their last 10 meetings.

In this Diamondbacks vs Giants Prediction, the Giants are coming as -185 home favorites. The Dbacks are going for a bullpen game, having the 5th-worst bullpen ERA in the league. On the flip side, the Giants are sending their ace on the mound on Logan Webb, who has been better at home, with a 2.85 ERA, and coming into this matchup in good form, with a 4-1 record and 2.87 ERA across his last 5 starts. The Giants also have the second-best bullpen in baseball to back him up, so I like them to get the job done at home today.

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